caa a22 4500 445311495 CHVBK 20180317142631.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00404-011-1934-6 doi (NATIONALLICENCE)springer-10.1007/s00404-011-1934-6 Invasive placentation and uterus preserving treatment modalities: a systematic review [Elektronische Daten] [Charlotte Steins Bisschop, Timme Schaap, Tatjana Vogelvang, Piet Scholten] Purpose: We present a systematic review to evaluate failure rates (secondary hysterectomy or maternal mortality) and success rates (subsequent menstruation or pregnancy) after different uterus preserving treatment modalities in women with invasive placentation. Methods: A review of English, German or Dutch language-published research, using Medline and Embase databases, was performed. Studies of any design were included. Results: Ten cohort studies and 50 case series or case reports were included. Expectant management reported a secondary hysterectomy in 55/287 (19%), maternal mortality in 1/295 (0.3%), a subsequent menstruation in 44/49 (90%) and a subsequent pregnancy in 24/36 (67%). Embolization of the uterine arteries described a secondary hysterectomy in 8/45 (18%), a subsequent menstruation in 8/13 (62%) and a subsequent pregnancy in 5/33 (15%). Methotrexate therapy presented a secondary hysterectomy in 1/16 (6%), a subsequent menstruation in 4/5 (80%) and a subsequent pregnancy in 1/2 (50%). Uterus preserving surgery showed a secondary hysterectomy in 24/77 (31%), maternal mortality in 2/55 (4%), a subsequent menstruation in 28/34 (82%) and a subsequent pregnancy in 19/26 (73%). Conclusions: This review indicates that different uterus preserving treatment modalities may be effective in managing invasive placentation. Despite the extensive review of the literature, no conclusions about the superiority of any modality can be drawn. The Author(s), 2011 Invasive placentation nationallicence Conservative management nationallicence Uterus preserving therapy nationallicence Systematic review nationallicence Steins Bisschop Charlotte Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Bosboomstraat 1, 80250, 3508 TG, Utrecht, The Netherlands aut Schaap Timme Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Bosboomstraat 1, 80250, 3508 TG, Utrecht, The Netherlands aut Vogelvang Tatjana Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Bosboomstraat 1, 80250, 3508 TG, Utrecht, The Netherlands aut Scholten Piet Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Bosboomstraat 1, 80250, 3508 TG, Utrecht, The Netherlands aut Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 491-502 0932-0067 284:2<491 2011 284 404 https://doi.org/10.1007/s00404-011-1934-6 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00404-011-1934-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Steins Bisschop Charlotte Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Bosboomstraat 1, 80250, 3508 TG, Utrecht, The Netherlands aut NATIONALLICENCE 700 1- Schaap Timme Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Bosboomstraat 1, 80250, 3508 TG, Utrecht, The Netherlands aut NATIONALLICENCE 700 1- Vogelvang Tatjana Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Bosboomstraat 1, 80250, 3508 TG, Utrecht, The Netherlands aut NATIONALLICENCE 700 1- Scholten Piet Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Bosboomstraat 1, 80250, 3508 TG, Utrecht, The Netherlands aut NATIONALLICENCE 773 0- Archives of Gynecology and Obstetrics Springer-Verlag 284/2(2011-08-01), 491-502 0932-0067 284:2<491 2011 284 404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer