caa a22 4500 445312831 CHVBK 20180317142636.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s11095-010-0285-5 doi (NATIONALLICENCE)springer-10.1007/s11095-010-0285-5 Biomagnetic Methods: Technologies Applied to Pharmaceutical Research [Elektronische Daten] [Luciana Corá, Madileine Américo, Ricardo Oliveira, Cristina Serra, Oswaldo Baffa, Raul Evangelista, Giselle Oliveira, José Miranda] ABSTRACT: Biomagnetic methods have been designed for a wide range of applications. Recently, such methods have been proposed as alternatives to scintigraphy for evaluating of a number of pharmaceutical processes in vitro as well as under the influence of gastrointestinal physiological parameters. In this review, physical characterization as well as the most recent applications of Superconducting Quantum Interference Device (SQUID), Anisotropic Magnetoresistive (AMR) and AC Biosusceptometry (ACB) in the pharmaceutical research will be explored. Moreover, their current status and how these technologies can be employed to improve the knowledge about the impact of gastrointestinal physiology on drug delivery in association with pharmacokinetic outcomes, termed pharmacomagnetography, will be presented. Springer Science+Business Media, LLC, 2010 drug delivery nationallicence gastrointestinal physiology nationallicence imaging nationallicence pharmacokinetic nationallicence solid dosage forms nationallicence Corá Luciana Pró-Reitoria de Pesquisa e Pós-graduação - PROPEP, Universidade Estadual de Ciências da Saúde de Alagoas—UNCISAL, Maceió, AL, Brazil aut Américo Madileine Instituto de Ciências Biológicas e da Saúde - ICBS, Universidade Federal de Mato Grosso—UFMT, Barra do Garças, MT, Brazil aut Oliveira Ricardo Dep. Clínica Médica—FMRP, Universidade de São Paulo—USP, Ribeirão Preto, SP, Brazil aut Serra Cristina Dep. Fármacos e Medicamentos—FCF, Universidade de São Paulo—USP, SP, São Paulo, Brazil aut Baffa Oswaldo Dep. Física e Matemática—FCFLRP, Universidade de São Paulo—USP, Ribeirão Preto, SP, Brazil aut Evangelista Raul Dep. Fármacos e Medicamentos—FCFAR, Universidade Estadual Paulista—UNESP, Araraquara, SP, Brazil aut Oliveira Giselle Dep. Fármacos e Medicamentos—FCFAR, Universidade Estadual Paulista—UNESP, Araraquara, SP, Brazil aut Miranda José Departmento de Física e Biofísica—Instituto de Biociências, IBB, Universidade Estadual Paulista—UNESP, Distrito Rubiao Jr, sn, PO Box510, 18600-000, Botucatu, Sao Paulo, Brazil aut Pharmaceutical Research Springer US; http://www.springer-ny.com 28/3(2011-03-01), 438-455 0724-8741 28:3<438 2011 28 11095 https://doi.org/10.1007/s11095-010-0285-5 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11095-010-0285-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Corá Luciana Pró-Reitoria de Pesquisa e Pós-graduação - PROPEP, Universidade Estadual de Ciências da Saúde de Alagoas—UNCISAL, Maceió, AL, Brazil aut NATIONALLICENCE 700 1- Américo Madileine Instituto de Ciências Biológicas e da Saúde - ICBS, Universidade Federal de Mato Grosso—UFMT, Barra do Garças, MT, Brazil aut NATIONALLICENCE 700 1- Oliveira Ricardo Dep. Clínica Médica—FMRP, Universidade de São Paulo—USP, Ribeirão Preto, SP, Brazil aut NATIONALLICENCE 700 1- Serra Cristina Dep. Fármacos e Medicamentos—FCF, Universidade de São Paulo—USP, SP, São Paulo, Brazil aut NATIONALLICENCE 700 1- Baffa Oswaldo Dep. Física e Matemática—FCFLRP, Universidade de São Paulo—USP, Ribeirão Preto, SP, Brazil aut NATIONALLICENCE 700 1- Evangelista Raul Dep. Fármacos e Medicamentos—FCFAR, Universidade Estadual Paulista—UNESP, Araraquara, SP, Brazil aut NATIONALLICENCE 700 1- Oliveira Giselle Dep. Fármacos e Medicamentos—FCFAR, Universidade Estadual Paulista—UNESP, Araraquara, SP, Brazil aut NATIONALLICENCE 700 1- Miranda José Departmento de Física e Biofísica—Instituto de Biociências, IBB, Universidade Estadual Paulista—UNESP, Distrito Rubiao Jr, sn, PO Box510, 18600-000, Botucatu, Sao Paulo, Brazil aut NATIONALLICENCE 773 0- Pharmaceutical Research Springer US; http://www.springer-ny.com 28/3(2011-03-01), 438-455 0724-8741 28:3<438 2011 28 11095 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer