caa a22 4500 445314664 CHVBK 20180317142642.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s10552-010-9663-x doi (NATIONALLICENCE)springer-10.1007/s10552-010-9663-x Complementary approaches to assessing risk factors for interval breast cancer [Elektronische Daten] [Jan Lowery, Tim Byers, John Hokanson, John Kittelson, John Lewin, Betsy Risendal, Meenakshi Singh, Judy Mouchawar] Objective: To examine risk factors for interval breast cancer among women screened in a population-based mammography program. Methods: Risk for interval cancer was assessed in terms of both the incidence per 10,000 negative screens and the proportion of all breast cancers diagnosed among screened women. Interval (N=557) and screen-detected cancers (N=1,545) were identified among 208,667 women receiving mammography in Colorado (1994-2001). Logistic regression was used to assess independent effects of multiple factors. Results: Overall risk of interval cancer was 29.5/10,000 women screened. Incidence was higher in women >50years (OR: 2.28, 1.86-2.80), with family history (OR: 2.23, 1.85-2.70), with dense breasts (OR: 3.84, 2.76-5.35), and using hormones (OR: 1.54, 1.20-1.97). Hispanics had lower incidence than Whites (OR: 0.52, 0.34-0.81). Interval cancers represented 26% of all cancers diagnosed. This proportion was higher in women <50 (OR: 1.41, 1.09-1.82) and in women with dense breasts (OR: 2.95, 1.94-4.48). Conclusions: Incidence of interval cancer increases with age, breast density, hormone use, and family history. Attempts to reduce occurrence of these cancers through more sensitive and/or intensive screening should focus on these subgroups. The disproportionate number of interval cancers associated with young age and dense breasts suggests these cancers result from both rapid growth and difficulties in detection. Springer Science+Business Media B.V., 2010 Interval breast cancer nationallicence Risk factor nationallicence Ethnicity nationallicence Family history nationallicence Lowery Jan Colorado School of Public Health, University of Colorado, Denver, CO, USA aut Byers Tim Colorado School of Public Health, University of Colorado, Denver, CO, USA aut Hokanson John Colorado School of Public Health, University of Colorado, Denver, CO, USA aut Kittelson John Colorado School of Public Health, University of Colorado, Denver, CO, USA aut Lewin John Diversified Radiology of Colorado, Denver, CO, USA aut Risendal Betsy Colorado School of Public Health, University of Colorado, Denver, CO, USA aut Singh Meenakshi Department of Pathology, State University of New York at Stony Brook, Stony Brook, NY, USA aut Mouchawar Judy Kaiser Permanente, Denver, CO, USA aut Cancer Causes & Control Springer Netherlands 22/1(2011-01-01), 23-31 0957-5243 22:1<23 2011 22 10552 https://doi.org/10.1007/s10552-010-9663-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-010-9663-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lowery Jan Colorado School of Public Health, University of Colorado, Denver, CO, USA aut NATIONALLICENCE 700 1- Byers Tim Colorado School of Public Health, University of Colorado, Denver, CO, USA aut NATIONALLICENCE 700 1- Hokanson John Colorado School of Public Health, University of Colorado, Denver, CO, USA aut NATIONALLICENCE 700 1- Kittelson John Colorado School of Public Health, University of Colorado, Denver, CO, USA aut NATIONALLICENCE 700 1- Lewin John Diversified Radiology of Colorado, Denver, CO, USA aut NATIONALLICENCE 700 1- Risendal Betsy Colorado School of Public Health, University of Colorado, Denver, CO, USA aut NATIONALLICENCE 700 1- Singh Meenakshi Department of Pathology, State University of New York at Stony Brook, Stony Brook, NY, USA aut NATIONALLICENCE 700 1- Mouchawar Judy Kaiser Permanente, Denver, CO, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/1(2011-01-01), 23-31 0957-5243 22:1<23 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer