caa a22 4500 445314761 CHVBK 20180317142642.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10552-011-9765-0 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9765-0 Drinking water fluoridation and osteosarcoma incidence on the island of Ireland [Elektronische Daten] [Harry Comber, Sandra Deady, Erin Montgomery, Anna Gavin] The incidence of osteosarcoma in Northern Ireland was compared with that in the Republic of Ireland to establish if differences in incidence between the two regions could be related to their different drinking water fluoridation policies. Data from the Northern Ireland Cancer Registry (NICR) and the National Cancer Registry of Ireland (NCRI) on osteosarcoma incidence in the respective populations were used to estimate the age-standardised and age-specific incidence rates in areas with and without drinking water fluoridation. One hundred and eighty-three osteosarcoma cases were recorded on the island of Ireland between 1994 and 2006. No significant differences were observed between fluoridated and non-fluoridated areas in either age-specific or age-standardised incidence rates of osteosarcoma. The results of this study do not support the hypothesis that osteosarcoma incidence in the island of Ireland is significantly related to public water fluoridation. However, this conclusion must be qualified, in view of the relative rarity of the cancer and the correspondingly wide confidence intervals of the relative risk estimates. Springer Science+Business Media B.V., 2011 Osteosarcoma nationallicence Fluoridation nationallicence Drinking water nationallicence Ireland nationallicence Comber Harry National Cancer Registry, Ireland, Cork Airport Business Park, Building 6800, Kinsale Road, Cork, Ireland aut Deady Sandra National Cancer Registry, Ireland, Cork Airport Business Park, Building 6800, Kinsale Road, Cork, Ireland aut Montgomery Erin Northern Ireland Statistics and Research Agency, McAuley House, 2-14 Castle Street, BT1 1SA, Belfast, Northern Ireland, UK aut Gavin Anna N. Ireland Cancer Registry, Centre for Public Health, Queen's University Belfast, Mulhouse Building, Grosvenor Road, Bt12 6BJ, Belfast, Northern Ireland, UK aut Cancer Causes & Control Springer Netherlands 22/6(2011-06-01), 919-924 0957-5243 22:6<919 2011 22 10552 https://doi.org/10.1007/s10552-011-9765-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9765-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Comber Harry National Cancer Registry, Ireland, Cork Airport Business Park, Building 6800, Kinsale Road, Cork, Ireland aut NATIONALLICENCE 700 1- Deady Sandra National Cancer Registry, Ireland, Cork Airport Business Park, Building 6800, Kinsale Road, Cork, Ireland aut NATIONALLICENCE 700 1- Montgomery Erin Northern Ireland Statistics and Research Agency, McAuley House, 2-14 Castle Street, BT1 1SA, Belfast, Northern Ireland, UK aut NATIONALLICENCE 700 1- Gavin Anna N. Ireland Cancer Registry, Centre for Public Health, Queen's University Belfast, Mulhouse Building, Grosvenor Road, Bt12 6BJ, Belfast, Northern Ireland, UK aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/6(2011-06-01), 919-924 0957-5243 22:6<919 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer