caa a22 4500 445315075 CHVBK 20180317142643.0 cr unu---uuuuu 170323e20110701xx s 000 0 eng 10.1007/s10552-011-9771-2 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9771-2 Green tea and coffee consumption and its association with thyroid cancer risk: a population-based cohort study in Japan [Elektronische Daten] [Takehiro Michikawa, Manami Inoue, Taichi Shimazu, Shizuka Sasazuki, Motoki Iwasaki, Norie Sawada, Taiki Yamaji, Shoichiro Tsugane] Background: The anticarcinogenic potential of green tea and coffee might be expected to reduce the risk of thyroid cancer, but epidemiological evidence is sparse. We examined green tea and coffee consumption in association with thyroid cancer risk in a general Japanese population. Methods: We analyzed data from a prospective cohort of 100,507 persons (48,802 men; 51,705 women) aged 40-69. Green tea and coffee consumption were assessed via a self-administered questionnaire. During a mean 14.2-year follow-up, we documented 159 thyroid cancer cases (26 in men; 133 in women), and Cox regression were used to calculated hazard ratios (HRs). Results: Green tea consumption was not found to be associated with thyroid cancer risk in general. However, when women were stratified by menopausal status, the multivariable HR for ≥5cups/day versus <1cup/day was 1.66 (95% confidence interval (CI)=0.85-3.23, trend p=0.04) in premenopausal women, and was 0.47 (95% CI=0.23-0.96, trend p=0.06) in postmenopausal women. We found no association between coffee consumption and thyroid cancer risk in either sex. Conclusions: High green tea consumption may be positively associated with premenopausal thyroid cancer risk, but inversely associated with postmenopausal thyroid cancer risk. Springer Science+Business Media B.V., 2011 Green tea nationallicence Coffee nationallicence Thyroid cancer nationallicence Menopausal status nationallicence Cohort study nationallicence Michikawa Takehiro Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut Inoue Manami Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut Shimazu Taichi Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut Sasazuki Shizuka Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut Iwasaki Motoki Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut Sawada Norie Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut Yamaji Taiki Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut Tsugane Shoichiro Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut Cancer Causes & Control Springer Netherlands 22/7(2011-07-01), 985-993 0957-5243 22:7<985 2011 22 10552 https://doi.org/10.1007/s10552-011-9771-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9771-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Michikawa Takehiro Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut NATIONALLICENCE 700 1- Inoue Manami Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut NATIONALLICENCE 700 1- Shimazu Taichi Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut NATIONALLICENCE 700 1- Sasazuki Shizuka Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut NATIONALLICENCE 700 1- Iwasaki Motoki Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut NATIONALLICENCE 700 1- Sawada Norie Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut NATIONALLICENCE 700 1- Yamaji Taiki Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut NATIONALLICENCE 700 1- Tsugane Shoichiro Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/7(2011-07-01), 985-993 0957-5243 22:7<985 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer