caa a22 4500 445315407 CHVBK 20180317142645.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s10552-010-9710-7 doi (NATIONALLICENCE)springer-10.1007/s10552-010-9710-7 Temporal trends in the black/white breast cancer case ratio for estrogen receptor status: disparities are historically contingent, not innate [Elektronische Daten] [Nancy Krieger, Jarvis Chen, Pamela Waterman] Objective: For at least three decades, many investigators have reported on the US black/white breast cancer case ratio for estrogen receptor (ER) status as if it reflected an intrinsic biological difference. In light of racial/ethnic differences in declines in the incidence of ER+ breast cancer, as linked to changing use of hormone therapy, we empirically tested whether the black/white breast cancer estrogen receptor ratio has changed over time. Methods: We examined temporal trends in the odds of being ER+ among white as compared to black women among all cases of invasive breast cancer occurring among women residing in the catchment area of the SEER 13 Registries Database between 1992 and 2005. Results: During the study period, the odds of being ER+ among the white compared to black cases increased from 1992 to 2002 (a statistically significant joinpoint; p<0.05; peak odds ratio (2002)=2.25 (95% confidence interval 2.13, 2.39)). Thereafter, the odds ratio leveled off (post-2002 slope not significantly different from zero; p=0.326). Among women aged 45-54, moreover, the post-2002 decline tended toward statistical significance (p=0.0891). Conclusions: The results suggest the black/white breast cancer case estrogen receptor ratio is historically contingent, not innate. Springer Science+Business Media B.V., 2010 Black nationallicence Breast cancer nationallicence Cancer disparities nationallicence Estrogen receptor nationallicence Social determinants of health nationallicence White nationallicence Krieger Nancy Department of Society, Human Development, and Health, Harvard School of Public Health, Kresge 717, 677 Huntington Avenue, 02115, Boston, MA, USA aut Chen Jarvis Department of Society, Human Development, and Health, Harvard School of Public Health, Kresge 717, 677 Huntington Avenue, 02115, Boston, MA, USA aut Waterman Pamela Department of Society, Human Development, and Health, Harvard School of Public Health, Kresge 717, 677 Huntington Avenue, 02115, Boston, MA, USA aut Cancer Causes & Control Springer Netherlands 22/3(2011-03-01), 511-514 0957-5243 22:3<511 2011 22 10552 https://doi.org/10.1007/s10552-010-9710-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-010-9710-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Krieger Nancy Department of Society, Human Development, and Health, Harvard School of Public Health, Kresge 717, 677 Huntington Avenue, 02115, Boston, MA, USA aut NATIONALLICENCE 700 1- Chen Jarvis Department of Society, Human Development, and Health, Harvard School of Public Health, Kresge 717, 677 Huntington Avenue, 02115, Boston, MA, USA aut NATIONALLICENCE 700 1- Waterman Pamela Department of Society, Human Development, and Health, Harvard School of Public Health, Kresge 717, 677 Huntington Avenue, 02115, Boston, MA, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/3(2011-03-01), 511-514 0957-5243 22:3<511 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer