caa a22 4500 445315601 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10552-011-9733-8 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9733-8 Reproductive and menstrual factors and mammographic density in African American, Caribbean, and white women [Elektronische Daten] [Parisa Tehranifar, Diane Reynolds, Julie Flom, Loralee Fulton, Yuyan Liao, Elizabeth Kudadjie-Gyamfi, Mary Terry] Objective: We investigated the associations between reproductive and menstrual risk factors for breast cancer and mammographic density, a strong risk factor for breast cancer, in a predominantly ethnic minority and immigrant sample. Methods: We interviewed women (42% African American, 22% African Caribbean, 22% White, 9% Hispanic Caribbean, 5% other) without a history of breast cancer during their mammography appointment (n=191, mean age=50). We used a computer-assisted method to measure the area and percentage of dense breast tissue from cranio-caudal mammograms. We used multivariable linear regression analyses to estimate the associations between reproductive and menstrual risk factors and mammographic density. Results: Age was inversely associated with percent density and dense area, and body mass index (BMI) was inversely associated with percent density. Adjusting for age, BMI, ethnicity and menopausal status, later age at menarche (e.g., β=−7.37, 95% CI: −12.29, −2.46 for age ≥13years vs. ≤11years), and any use of hormonal birth control (HBC) methods (β=−5.10, 95% CI: −9.37, −0.84) were associated with reduced dense area. Ethnicity and nativity (foreign- vs. US-born) were not directly associated with density despite variations in the distribution of several risk factors across ethnic and nativity groups. Conclusions: The mean level of mammographic density did not differ across ethnic and nativity groups, but several risk factors for breast cancer were associated with density in ethnic minority and immigrant women. Springer Science+Business Media B.V., 2011 Breast cancer nationallicence Mammographic density nationallicence Risk factors nationallicence Ethnicity nationallicence Nativity status nationallicence Tehranifar Parisa Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, 10032, New York, NY, USA aut Reynolds Diane School of Nursing, Long Island University, Brooklyn Campus, Brooklyn, NY, USA aut Flom Julie Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, 10032, New York, NY, USA aut Fulton Loralee Othmer Cancer Center, Long Island College Hospital, Brooklyn, NY, USA aut Liao Yuyan Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, 10032, New York, NY, USA aut Kudadjie-Gyamfi Elizabeth Department of Psychology, Long Island University, Brooklyn Campus, Brooklyn, NY, USA aut Terry Mary Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, 10032, New York, NY, USA aut Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 599-610 0957-5243 22:4<599 2011 22 10552 https://doi.org/10.1007/s10552-011-9733-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9733-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tehranifar Parisa Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, 10032, New York, NY, USA aut NATIONALLICENCE 700 1- Reynolds Diane School of Nursing, Long Island University, Brooklyn Campus, Brooklyn, NY, USA aut NATIONALLICENCE 700 1- Flom Julie Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, 10032, New York, NY, USA aut NATIONALLICENCE 700 1- Fulton Loralee Othmer Cancer Center, Long Island College Hospital, Brooklyn, NY, USA aut NATIONALLICENCE 700 1- Liao Yuyan Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, 10032, New York, NY, USA aut NATIONALLICENCE 700 1- Kudadjie-Gyamfi Elizabeth Department of Psychology, Long Island University, Brooklyn Campus, Brooklyn, NY, USA aut NATIONALLICENCE 700 1- Terry Mary Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, 10032, New York, NY, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 599-610 0957-5243 22:4<599 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer