caa a22 4500 445315628 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10552-011-9737-4 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9737-4 Smoking and alcohol drinking increased the risk of esophageal cancer among Chinese men but not women in a high-risk population [Elektronische Daten] [Ming Wu, Jin-Kou Zhao, Zuo-Feng Zhang, Ren-Qiang Han, Jie Yang, Jin-Yi Zhou, Xu-Shan Wang, Xiao-Feng Zhang, Ai-Min Liu, Pieter van' t Veer, Frans Kok, Ellen Kampman] Although the association for esophageal cancer with tobacco smoking and alcohol drinking has been well established, the risk appears to be less strong in China. To provide more evidence on the effect of smoking and alcohol consumption with esophageal cancer in China, particularly among Chinese women, a population-based case-control study has been conducted in Jiangsu, China, from 2003 to 2007. A total of 1,520 cases and 3,879 controls were recruited. Unconditional multivariate logistic regression analysis was applied. Results showed that the odds ratio (OR) and confidence interval (CI) for ever smoking and alcohol drinking were 1.57 (95% CI: 1.34-1.83) and 1.50 (95% CI: 1.29-1.74). Dose-response relationships were observed with increased intensity and longer duration of smoking/drinking. Risk of smoking and alcohol drinking at the highest joint level was 7.32 (95% CI: 4.58-11.7), when compared to those never smoked and never drank alcohol. Stratifying by genders, smoking and alcohol drinking increased the risk among men with an OR of 1.74 (95% CI: 1.44-2.09) and 1.76 (95% CI: 1.48-2.09); however, neither smoking nor alcohol consumption showed a significant association among women. In conclusion, smoking and alcohol drinking were associated with esophageal cancer risk among Chinese men, but not among Chinese women. The Author(s), 2011 Esophageal cancer nationallicence Smoking nationallicence Alcohol nationallicence Case-control studies nationallicence China nationallicence Wu Ming Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut Zhao Jin-Kou Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut Zhang Zuo-Feng Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA, USA aut Han Ren-Qiang Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut Yang Jie Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut Zhou Jin-Yi Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut Wang Xu-Shan Ganyu Center for Disease Control and Prevention, Ganyu, Jiangsu, China aut Zhang Xiao-Feng Ganyu Center for Disease Control and Prevention, Ganyu, Jiangsu, China aut Liu Ai-Min Dafeng Center for Disease Control and Prevention, Dafeng, Jiangsu, China aut van' t Veer Pieter Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands aut Kok Frans Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands aut Kampman Ellen Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands aut Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 649-657 0957-5243 22:4<649 2011 22 10552 https://doi.org/10.1007/s10552-011-9737-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9737-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wu Ming Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut NATIONALLICENCE 700 1- Zhao Jin-Kou Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut NATIONALLICENCE 700 1- Zhang Zuo-Feng Department of Epidemiology, School of Public Health, University of California, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Han Ren-Qiang Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut NATIONALLICENCE 700 1- Yang Jie Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut NATIONALLICENCE 700 1- Zhou Jin-Yi Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, 210009, Nanjing, Jiangsu, China aut NATIONALLICENCE 700 1- Wang Xu-Shan Ganyu Center for Disease Control and Prevention, Ganyu, Jiangsu, China aut NATIONALLICENCE 700 1- Zhang Xiao-Feng Ganyu Center for Disease Control and Prevention, Ganyu, Jiangsu, China aut NATIONALLICENCE 700 1- Liu Ai-Min Dafeng Center for Disease Control and Prevention, Dafeng, Jiangsu, China aut NATIONALLICENCE 700 1- van' t Veer Pieter Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands aut NATIONALLICENCE 700 1- Kok Frans Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands aut NATIONALLICENCE 700 1- Kampman Ellen Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 649-657 0957-5243 22:4<649 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer