caa a22 4500 445315644 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10552-011-9729-4 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9729-4 Estrogens in the breast tissue: a systematic review [Elektronische Daten] [Lusine Yaghjyan, Graham Colditz] The role of estrogens in breast carcinogenesis has been investigated at the level of whole body (plasma) and cell (molecular, receptors, etc.). Growing attention focused on the breast tissue being an intracrine organ, with potentially important local estrogen production in the breast. However, very little is known about the local breast tissue estrogen levels. Understanding the role of the tissue estrogens in breast carcinogenesis might open new avenues in breast cancer prevention. This systematic review summarizes published studies that measured local estrogen levels in the breast and offers suggestions for strategies to fill gaps in our existing scientific knowledge. Springer Science+Business Media B.V., 2011 Estrogen metabolites nationallicence Tissue estrogen metabolism nationallicence Breast carcinogenesis nationallicence BMI : Body mass index nationallicence CV : Coefficient of variation nationallicence LPAT : Laboratory of proteomics and analytical technologies nationallicence MS : Mass spectrometry nationallicence NCI : National Cancer Institute nationallicence Yaghjyan Lusine Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis School of Medicine, Campus Box 8100, 660 S. Euclid Avenue, 63110, St. Louis, MO, USA aut Colditz Graham Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis School of Medicine, Campus Box 8100, 660 S. Euclid Avenue, 63110, St. Louis, MO, USA aut Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 529-540 0957-5243 22:4<529 2011 22 10552 https://doi.org/10.1007/s10552-011-9729-4 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9729-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yaghjyan Lusine Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis School of Medicine, Campus Box 8100, 660 S. Euclid Avenue, 63110, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Colditz Graham Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis School of Medicine, Campus Box 8100, 660 S. Euclid Avenue, 63110, St. Louis, MO, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 529-540 0957-5243 22:4<529 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer