caa a22 4500 445315660 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10552-011-9732-9 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9732-9 Postdiagnosis diet quality, the combination of diet quality and recreational physical activity, and prognosis after early-stage breast cancer [Elektronische Daten] [Stephanie George, Melinda Irwin, Ashley Smith, Marian Neuhouser, Jill Reedy, Anne McTiernan, Catherine Alfano, Leslie Bernstein, Cornelia Ulrich, Kathy Baumgartner, Steven Moore, Demetrius Albanes, Susan Mayne, Mitchell Gail, Rachel Ballard-Barbash] Objective: To investigate, among women with breast cancer, how postdiagnosis diet quality and the combination of diet quality and recreational physical activity are associated with prognosis. Methods: This multiethnic, prospective observational cohort included 670 women diagnosed with local or regional breast cancer. Thirty months after diagnosis, women completed self-report assessments on diet and physical activity and were followed for 6years. Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals for death from any cause and breast cancer death. Results: Women consuming better-quality diets, as defined by higher Healthy Eating Index-2005 scores, had a 60% reduced risk of death from any cause (HRQ4:Q1: 0.40, 95% CI: 0.17, 0.94) and an 88% reduced risk of death from breast cancer (HRQ4:Q1: 0.12, 95% CI: 0.02, 0.99). Compared with inactive survivors consuming poor-quality diets, survivors engaging in any recreational physical activity and consuming better-quality diets had an 89% reduced risk of death from any cause (HR: 0.11, 95% CI: 0.04, 0.36) and a 91% reduced risk of death from breast cancer (HR: 0.09, 95% CI: 0.01, 0.89). Associations observed were independent of obesity status. Conclusion: Women diagnosed with localized or regional breast cancer may improve prognosis by adopting better-quality dietary patterns and regular recreational physical activity. Lifestyle interventions emphasizing postdiagnosis behavior changes are advisable in breast cancer survivors. Springer Science+Business Media B.V. (outside the USA), 2011 Diet nationallicence Exercise nationallicence Breast neoplasm nationallicence Prognosis nationallicence George Stephanie Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Suite 320, MSC 7232, 20852, Rockville, MD, USA aut Irwin Melinda Division of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA aut Smith Ashley Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut Neuhouser Marian Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA aut Reedy Jill Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut McTiernan Anne Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA aut Alfano Catherine Office of Cancer Survivorship, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut Bernstein Leslie Department of Population Sciences, City of Hope Medical Center and Beckman Research Center, Duarte, CA, USA aut Ulrich Cornelia Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA aut Baumgartner Kathy Department of Epidemiology and Population Health, University of Louisville, Louisville, KY, USA aut Moore Steven Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Suite 320, MSC 7232, 20852, Rockville, MD, USA aut Albanes Demetrius Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Suite 320, MSC 7232, 20852, Rockville, MD, USA aut Mayne Susan Division of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA aut Gail Mitchell Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA aut Ballard-Barbash Rachel Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 589-598 0957-5243 22:4<589 2011 22 10552 https://doi.org/10.1007/s10552-011-9732-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9732-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- George Stephanie Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Suite 320, MSC 7232, 20852, Rockville, MD, USA aut NATIONALLICENCE 700 1- Irwin Melinda Division of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA aut NATIONALLICENCE 700 1- Smith Ashley Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut NATIONALLICENCE 700 1- Neuhouser Marian Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA aut NATIONALLICENCE 700 1- Reedy Jill Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut NATIONALLICENCE 700 1- McTiernan Anne Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA aut NATIONALLICENCE 700 1- Alfano Catherine Office of Cancer Survivorship, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut NATIONALLICENCE 700 1- Bernstein Leslie Department of Population Sciences, City of Hope Medical Center and Beckman Research Center, Duarte, CA, USA aut NATIONALLICENCE 700 1- Ulrich Cornelia Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA aut NATIONALLICENCE 700 1- Baumgartner Kathy Department of Epidemiology and Population Health, University of Louisville, Louisville, KY, USA aut NATIONALLICENCE 700 1- Moore Steven Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Suite 320, MSC 7232, 20852, Rockville, MD, USA aut NATIONALLICENCE 700 1- Albanes Demetrius Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Suite 320, MSC 7232, 20852, Rockville, MD, USA aut NATIONALLICENCE 700 1- Mayne Susan Division of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA aut NATIONALLICENCE 700 1- Gail Mitchell Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA aut NATIONALLICENCE 700 1- Ballard-Barbash Rachel Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 589-598 0957-5243 22:4<589 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer