caa a22 4500 445315695 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10552-011-9738-3 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9738-3 Abuse victimization and risk of breast cancer in the Black Women's Health Study [Elektronische Daten] Abuse and breast cancer risk in black women [Lauren Wise, Julie Palmer, Deborah Boggs, Lucile Adams-Campbell, Lynn Rosenberg] Few studies have examined the relation between abuse victimization and breast cancer, and results have been inconclusive. Using data from 35,728 participants in the Black Women's Health Study, we conducted multivariable Cox regression to estimate incidence rate ratios (IRRs) and 95% confidence intervals (CI) for the association of abuse across the life span (childhood, adolescence, and adulthood) with breast cancer. Incident breast cancer diagnoses were reported during 1995-2009, and abuse histories were reported in 2005. No associations were found between abuse victimization in either childhood or adolescence and breast cancer. We found a weak positive association between abuse in adulthood and breast cancer (IRR=1.18, 95% CI=1.03-1.34). IRRs for physical abuse only, sexual abuse only, and both physical and sexual abuse in adulthood, relative to no abuse, were 1.28 (95% CI=1.09-1.49), 0.96 (95% CI=0.76-1.20), and 1.22 (95% CI=1.00-1.49), respectively. IRRs for low, intermediate, and high frequencies of physical abuse in adulthood, relative to no abuse, were 1.28 (95% CI=1.07-1.52), 1.37 (95% CI=1.04-1.79), and 1.24 (95% CI=0.95-1.62), respectively. Our data suggest an increased risk of breast cancer among African-American women who reported physical abuse in adulthood, but there was little evidence of a dose-response relation. These results require confirmation in other studies. Springer Science+Business Media B.V., 2011 Breast cancer nationallicence Violence nationallicence African-American nationallicence Females nationallicence Risk factors nationallicence Wise Lauren Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, 02215, Boston, MA, USA aut Palmer Julie Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, 02215, Boston, MA, USA aut Boggs Deborah Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, 02215, Boston, MA, USA aut Adams-Campbell Lucile Lombardi Comprehensive Cancer Center, Georgetown University, 20057, Washington, DC, USA aut Rosenberg Lynn Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, 02215, Boston, MA, USA aut Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 659-669 0957-5243 22:4<659 2011 22 10552 https://doi.org/10.1007/s10552-011-9738-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9738-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wise Lauren Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, 02215, Boston, MA, USA aut NATIONALLICENCE 700 1- Palmer Julie Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, 02215, Boston, MA, USA aut NATIONALLICENCE 700 1- Boggs Deborah Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, 02215, Boston, MA, USA aut NATIONALLICENCE 700 1- Adams-Campbell Lucile Lombardi Comprehensive Cancer Center, Georgetown University, 20057, Washington, DC, USA aut NATIONALLICENCE 700 1- Rosenberg Lynn Slone Epidemiology Center, Boston University, 1010 Commonwealth Avenue, 02215, Boston, MA, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/4(2011-04-01), 659-669 0957-5243 22:4<659 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer