caa a22 4500 445315717 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10552-011-9789-5 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9789-5 Intake of whole-grain products and risk of prostate cancer among men in the Danish Diet, Cancer and Health cohort study [Elektronische Daten] [Rikke Egeberg, Anja Olsen, Jane Christensen, Nina Johnsen, Steffen Loft, Kim Overvad, Anne Tjønneland] Objective: High intake of whole-grain products may protect against prostate cancer, but overall evidence is limited and inconclusive. The aim of the present study was to investigate the relationship between the intake of whole-grain products and risk of prostate cancer in a large prospective cohort. Methods: A total of 26,691 men aged 50-64years participated in the Diet, Cancer and Health cohort study and provided information about diet and potential prostate cancer risk factors. During a median follow-up of 12.4years, we identified 1,081 prostate cancer cases. Associations between whole-grain product intake and prostate cancer incidence were analyzed using Cox's regression model. Results: Overall, there was no association between total intake of whole-grain products and prostate cancer risk (adjusted incidence rate ratio per 50gday−1: 1.00 (95% confidence interval: 0.96, 1.05)) as well as between intake of the specific whole-grain products: whole-grain rye bread, whole-grain bread, and oatmeal, and risk of prostate cancer. No risk estimates did differ according to either stage or grade of disease. Conclusions: Results from this prospective study suggest that higher intakes of total or specific whole-grain products are not associated with risk of prostate cancer in a population of Danish middle-aged men. Springer Science+Business Media B.V., 2011 Whole-grain products nationallicence Prostate cancer nationallicence Prospective study nationallicence Egeberg Rikke Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut Olsen Anja Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut Christensen Jane Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut Johnsen Nina Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut Loft Steffen Institute of Public Health, University of Copenhagen, Copenhagen, Denmark aut Overvad Kim Department of Epidemiology, School of Public Health, Aarhus University, Aarhus, Denmark aut Tjønneland Anne Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut Cancer Causes & Control Springer Netherlands 22/8(2011-08-01), 1133-1139 0957-5243 22:8<1133 2011 22 10552 https://doi.org/10.1007/s10552-011-9789-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9789-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Egeberg Rikke Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Olsen Anja Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Christensen Jane Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Johnsen Nina Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Loft Steffen Institute of Public Health, University of Copenhagen, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Overvad Kim Department of Epidemiology, School of Public Health, Aarhus University, Aarhus, Denmark aut NATIONALLICENCE 700 1- Tjønneland Anne Institute of Cancer Epidemiology, The Danish Cancer Society, Strandboulevarden 49, DK-2100, Copenhagen, Denmark aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/8(2011-08-01), 1133-1139 0957-5243 22:8<1133 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer