caa a22 4500 445315792 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10552-011-9797-5 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9797-5 Dietary intake of fruit and vegetables and risk of non-Hodgkin lymphoma [Elektronische Daten] [Brian Chiu, Soyang Kwon, Andrew Evens, Tanya Surawicz, Sonali Smith, Dennis Weisenburger] Objective: Few studies have evaluated the potential association between consumption of fruit and vegetables and non-Hodgkin lymphoma (NHL) by histologic subtype, and the results of these studies have been inconsistent. Methods: A detailed history of dietary practices and food preferences was collected using a food frequency questionnaire from 348 cases and 470 controls in a population-based, case-control study conducted in Nebraska during 1999-2002. Risk for the highest versus lowest quartile or tertile of intake was estimated by odds ratios (ORs) and 95% confidence interval (CIs). Results: A lower risk of overall NHL was associated with a high intake of green leafy vegetables (OR=0.6; CI=0.3-1.0) and cruciferous vegetables (OR=0.7; CI=0.4-1.0). Analysis by subtype showed that green leafy vegetable intake was associated with a lower risk of follicular lymphoma (OR=0.5; CI=0.3-0.8) and diffuse large B-cell lymphoma (DLBCL) (OR=0.5; CI=0.3-0.9), while consumption of cruciferous vegetables was associated with a lower risk of DLBCL (OR=0.4; CI=0.2-0.8). No association was found with intake of total vegetables, carotene-rich vegetables, or all fruit. For nutrients, the risk of NHL overall was inversely associated with a higher intake of β-cryptoxanthin (OR=0.6; CI=0.4-0.9), magnesium (OR=0.4; CI=0.2-0.6), potassium (OR=0.5; CI=0.3-1.0), and fiber (OR=0.6; CI=0.3-1.0), but positively associated with a higher intake of retinol (OR=1.7; CI=1.1-2.8). Intakes of vitamin E, magnesium, and potassium were inversely associated with the risk of DLBCL. Conclusion: A higher intake of green leafy vegetables and cruciferous vegetables is associated with a lower risk of NHL overall, particularly follicular lymphoma and DLBCL. Springer Science+Business Media B.V., 2011 Non-Hodgkin lymphoma nationallicence Diet nationallicence Vegetables nationallicence Antioxidants nationallicence Chiu Brian Department of Health Studies, University of Chicago, 5841 South Maryland Avenue, MC 2007, 60637, Chicago, IL, USA aut Kwon Soyang Department of Health Studies, University of Chicago, 5841 South Maryland Avenue, MC 2007, 60637, Chicago, IL, USA aut Evens Andrew Division of Hematology/Oncology Lymphoma Program, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut Surawicz Tanya Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut Smith Sonali University of Chicago Comprehensive Cancer Center, Chicago, IL, USA aut Weisenburger Dennis Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA aut Cancer Causes & Control Springer Netherlands 22/8(2011-08-01), 1183-1195 0957-5243 22:8<1183 2011 22 10552 https://doi.org/10.1007/s10552-011-9797-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9797-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chiu Brian Department of Health Studies, University of Chicago, 5841 South Maryland Avenue, MC 2007, 60637, Chicago, IL, USA aut NATIONALLICENCE 700 1- Kwon Soyang Department of Health Studies, University of Chicago, 5841 South Maryland Avenue, MC 2007, 60637, Chicago, IL, USA aut NATIONALLICENCE 700 1- Evens Andrew Division of Hematology/Oncology Lymphoma Program, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut NATIONALLICENCE 700 1- Surawicz Tanya Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut NATIONALLICENCE 700 1- Smith Sonali University of Chicago Comprehensive Cancer Center, Chicago, IL, USA aut NATIONALLICENCE 700 1- Weisenburger Dennis Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/8(2011-08-01), 1183-1195 0957-5243 22:8<1183 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer