caa a22 4500 445315806 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10552-011-9784-x doi (NATIONALLICENCE)springer-10.1007/s10552-011-9784-x The effect of marital status on stage and survival of prostate cancer patients treated with radical prostatectomy: a population-based study [Elektronische Daten] [Firas Abdollah, Maxine Sun, Rodolphe Thuret, Al'a Abdo, Monica Morgan, Claudio Jeldres, Shahrokh Shariat, Paul Perrotte, Francesco Montorsi, Pierre Karakiewicz] Objective: The detrimental effect of unmarried marital status on stage and survival has been confirmed in several malignancies. We set to test whether this applied to patients diagnosed with prostate cancer (PCa) treated with radical prostatectomy (RP). Methods: We identified 163,697 non-metastatic PCa patients treated with RP, within 17 Surveillance, Epidemiology, and End Results registries. Logistic regression analyses focused on the rate of locally advanced stage (pT3-4/pN1) at RP. Cox regression analyses tested the relationship between marital status and cancer-specific (CSM), as well as all-cause mortality (ACM). Results: Respectively, 9.1 and 7.8% of individuals were separated/divorced/widowed (SDW) and never married. SDW men had more advanced stage at surgery (odds ratio: 1.1; p<0.001), higher CSM and ACM (both hazard ratio [HR]: 1.3; p<0.001) than married men. Similarly, never married marital status portended to a higher ACM rate (HR:1.2, p=0.001). These findings were consistent when analyses were stratified according to organ confined vs. locally advanced stages. Conclusions: Being SDW significantly increased the risk of more advanced stage at RP. Following surgery, SDW men portended to a higher CSM and ACM rate than married men. Consequently, these individuals may benefit from a more focused health care throughout the natural history of their disease. Springer Science+Business Media B.V., 2011 Marital status nationallicence Neoplasm staging nationallicence Prostatic neoplasms/epidemiology nationallicence SEER program nationallicence Survival rates/trends nationallicence Abdollah Firas Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut Sun Maxine Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut Thuret Rodolphe Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut Abdo Al'a Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut Morgan Monica Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut Jeldres Claudio Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut Shariat Shahrokh Department of Urology, Weill Medical College of Cornell University, New York, NY, USA aut Perrotte Paul Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut Montorsi Francesco Department of Urology, Vita Salute University/San Raffaele Hospital, Milan, Italy aut Karakiewicz Pierre Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut Cancer Causes & Control Springer Netherlands 22/8(2011-08-01), 1085-1095 0957-5243 22:8<1085 2011 22 10552 https://doi.org/10.1007/s10552-011-9784-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9784-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Abdollah Firas Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Sun Maxine Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Thuret Rodolphe Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Abdo Al'a Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Morgan Monica Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Jeldres Claudio Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Shariat Shahrokh Department of Urology, Weill Medical College of Cornell University, New York, NY, USA aut NATIONALLICENCE 700 1- Perrotte Paul Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Montorsi Francesco Department of Urology, Vita Salute University/San Raffaele Hospital, Milan, Italy aut NATIONALLICENCE 700 1- Karakiewicz Pierre Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, H2X 3J4, Montreal, QC, Canada aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/8(2011-08-01), 1085-1095 0957-5243 22:8<1085 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer