caa a22 4500 445315822 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10552-011-9796-6 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9796-6 Temporal trends in geographic disparities in small-area-level colorectal cancer incidence and mortality in the United States [Elektronische Daten] [Mario Schootman, Min Lian, Anjali Deshpande, Amy McQueen, Sandi Pruitt, Donna Jeffe] Objective: We examined the extent of changes in absolute and relative geographic disparities in six colorectal cancer (CRC) indicators using data about persons aged 50 and older from 195 counties in the 1988-2006 Surveillance, Epidemiology, and End Results Program database. Methods: County-level trends in six colorectal cancer indicators (overall CRC incidence, descending colon cancer incidence, proximal colon cancer incidence, late-stage CRC incidence, CRC mortality, and 5-year probability of CRC death) were summarized using the estimated annual percentage change. Observed county rates were smoothed using Bayesian hierarchical spatiotemporal methods to calculate measures of absolute and relative geographic disparity and their changes over time. Results: During the study period, absolute disparity for all six indicators decreased (CRC incidence: 43.2%; proximal colon cancer: 31.9%; descending colon cancer: 52.8%; late-stage CRC: 50.0%; CRC mortality: 57.8%; 5-year CRC-specific probability of death: 12.2%). Relative disparity remained stable for all six indicators over the entire study period. Conclusion: Important progress has been made toward achieving the Healthy People 2010 and NCI strategic objectives for reducing geographic disparities, although absolute and relative disparities remain in CRC. Springer Science+Business Media B.V., 2011 Geography nationallicence Colon and rectal cancer nationallicence Bayesian models nationallicence Disparity nationallicence Schootman Mario Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut Lian Min Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut Deshpande Anjali Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut McQueen Amy Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut Pruitt Sandi Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut Jeffe Donna Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut Cancer Causes & Control Springer Netherlands 22/8(2011-08-01), 1173-1181 0957-5243 22:8<1173 2011 22 10552 https://doi.org/10.1007/s10552-011-9796-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9796-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Schootman Mario Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut NATIONALLICENCE 700 1- Lian Min Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut NATIONALLICENCE 700 1- Deshpande Anjali Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut NATIONALLICENCE 700 1- McQueen Amy Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut NATIONALLICENCE 700 1- Pruitt Sandi Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut NATIONALLICENCE 700 1- Jeffe Donna Department of Medicine, Division of Health Behavior Research, Washington University School of Medicine, Saint Louis, MO, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/8(2011-08-01), 1173-1181 0957-5243 22:8<1173 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer