caa a22 4500 445315857 CHVBK 20180317142646.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s10552-011-9748-1 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9748-1 Oropharyngeal cancer incidence trends: diminishing racial disparities [Elektronische Daten] [Linda Brown, David Check, Susan Devesa] Objective: The aim of this article is to evaluate oral cavity/pharyngeal cancer (OCPC) trends that may reflect changes in cigarette smoking, alcohol consumption, and human papillomavirus (HPV) infection. Methods: We used Surveillance, Epidemiology, and End Results program data for 58,204 cases diagnosed during 1977-2007 to classify if squamous cell carcinomas of the OCP by anatomic site are potentially HPV-related. Results: OCPC rates among men peaked during 1982-1986 before declining, most rapidly (46%) among blacks. Rates decreased least rapidly among white males while declining at intermediate paces among other ethnic groups (Asian/Pacific Islanders and Hispanics) and females. Among the men during the recent 16-year time period, the annual percent change for HPV-unrelated sites was much steeper [−6.0% (95% CI=−7.2 to −4.9)] among blacks than whites [−2.5% (95% CI=−2.9 to −2.1)]; for HPV-related sites, it was −1.7% (95% CI=−2.6 to −0.7) among blacks, in striking contrast to +3.3% (95% CI=2.5-4.0) among whites. HPV-related rates rose rapidly among the white men born since the mid-1940s, tripling among those aged 25-44 and recently surpassing the black male rate. Relative survival rates rose over the study period due to improvements among HPV-related cases. Conclusions: The OCPC decreases found among all the race/sex groups reflect reductions in smoking prevalence and alcohol consumption. Rising HPV-related cancers among white men may reflect changes in sexual practices since the mid-1960s. Springer Science+Business Media B.V. (outside the USA), 2011 Oropharyngeal cancer nationallicence Human papillomavirus (HPV) nationallicence Descriptive epidemiology nationallicence Incidence nationallicence Health disparities nationallicence Brown Linda RTI International, 6110 Executive Blvd., Suite 902, 20852-3907, Rockville, MD, USA aut Check David Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA aut Devesa Susan Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA aut Cancer Causes & Control Springer Netherlands 22/5(2011-05-01), 753-763 0957-5243 22:5<753 2011 22 10552 https://doi.org/10.1007/s10552-011-9748-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9748-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Brown Linda RTI International, 6110 Executive Blvd., Suite 902, 20852-3907, Rockville, MD, USA aut NATIONALLICENCE 700 1- Check David Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Devesa Susan Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/5(2011-05-01), 753-763 0957-5243 22:5<753 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer