caa a22 4500 44531589X CHVBK 20180317142647.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s10552-011-9742-7 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9742-7 Brain tumors and hormonal factors: review of the epidemiological literature [Elektronische Daten] [Anne Cowppli-Bony, Ghislaine Bouvier, Marjory Rué, Hugues Loiseau, Anne Vital, Pierre Lebailly, Pascale Fabbro-Peray, Isabelle Baldi] Background: To date, the etiology of primary tumors of the central nervous system (mainly gliomas and meningiomas) is poorly understood. The role of sex hormones has been suggested, based on clinical, experimental, biological, and epidemiological data. Objective: To review the epidemiological studies on the relation between hormonal factors and the occurrence of glioma and meningioma, in order to identify new research developments. Methods: Articles published until September 2010 were selected by considering exogenous and endogenous exposures and specific brain tumors. Standardized information was collected from 20 articles: 15 concerning gliomas and 13 meningiomas. Results: An increased glioma risk was observed with later menarche and menopause, while a reduced glioma risk was observed with hormone replacement therapy (HRT) and oral contraceptive use, despite duration of use had no effect on risk. Meningioma risk increased after menopause and with HRT use. No clear association was found with pregnancy and breastfeeding. Conclusion: Results are globally concordant with the biologic hypothesis assuming that female sex hormones are protective against glioma and may increase the risk of meningioma. However, new epidemiological studies should be conducted in order to confirm these associations and to refine the role of hormonal factors in brain etiology. Springer Science+Business Media B.V., 2011 Glioma nationallicence Meningioma nationallicence Reproductive history nationallicence Hormonal replacement therapy nationallicence Oral contraceptive nationallicence Cowppli-Bony Anne Laboratoire Santé Travail Environnement, Institut de Santé Publique d'Epidémiologie et de Développement, IFR 99, Université Victor Segalen Bordeaux 2, 146 rue Léo Saignat, 33076, Bordeaux Cedex, France aut Bouvier Ghislaine Laboratoire Santé Travail Environnement, Institut de Santé Publique d'Epidémiologie et de Développement, IFR 99, Université Victor Segalen Bordeaux 2, 146 rue Léo Saignat, 33076, Bordeaux Cedex, France aut Rué Marjory Service de neurochirurgie, CHU Pellegrin, Université Victor Segalen Bordeaux 2, Bordeaux, France aut Loiseau Hugues Service de neurochirurgie, CHU Pellegrin, Université Victor Segalen Bordeaux 2, Bordeaux, France aut Vital Anne Service de Pathologie, Centre Hospitalier et Universitaire de Bordeaux, Bordeaux, France aut Lebailly Pierre GRECAN, Centre François Baclesse, Université de Caen-Basse Normandie, Caen, France aut Fabbro-Peray Pascale Unité de Biostatistiques Epidémiologie, Institut Universitaire de Recherche Clinique, Université de Montpellier I, Montpellier, France aut Baldi Isabelle Laboratoire Santé Travail Environnement, Institut de Santé Publique d'Epidémiologie et de Développement, IFR 99, Université Victor Segalen Bordeaux 2, 146 rue Léo Saignat, 33076, Bordeaux Cedex, France aut Cancer Causes & Control Springer Netherlands 22/5(2011-05-01), 697-714 0957-5243 22:5<697 2011 22 10552 https://doi.org/10.1007/s10552-011-9742-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9742-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cowppli-Bony Anne Laboratoire Santé Travail Environnement, Institut de Santé Publique d'Epidémiologie et de Développement, IFR 99, Université Victor Segalen Bordeaux 2, 146 rue Léo Saignat, 33076, Bordeaux Cedex, France aut NATIONALLICENCE 700 1- Bouvier Ghislaine Laboratoire Santé Travail Environnement, Institut de Santé Publique d'Epidémiologie et de Développement, IFR 99, Université Victor Segalen Bordeaux 2, 146 rue Léo Saignat, 33076, Bordeaux Cedex, France aut NATIONALLICENCE 700 1- Rué Marjory Service de neurochirurgie, CHU Pellegrin, Université Victor Segalen Bordeaux 2, Bordeaux, France aut NATIONALLICENCE 700 1- Loiseau Hugues Service de neurochirurgie, CHU Pellegrin, Université Victor Segalen Bordeaux 2, Bordeaux, France aut NATIONALLICENCE 700 1- Vital Anne Service de Pathologie, Centre Hospitalier et Universitaire de Bordeaux, Bordeaux, France aut NATIONALLICENCE 700 1- Lebailly Pierre GRECAN, Centre François Baclesse, Université de Caen-Basse Normandie, Caen, France aut NATIONALLICENCE 700 1- Fabbro-Peray Pascale Unité de Biostatistiques Epidémiologie, Institut Universitaire de Recherche Clinique, Université de Montpellier I, Montpellier, France aut NATIONALLICENCE 700 1- Baldi Isabelle Laboratoire Santé Travail Environnement, Institut de Santé Publique d'Epidémiologie et de Développement, IFR 99, Université Victor Segalen Bordeaux 2, 146 rue Léo Saignat, 33076, Bordeaux Cedex, France aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/5(2011-05-01), 697-714 0957-5243 22:5<697 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer