caa a22 4500 445316098 CHVBK 20180317142647.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10552-010-9688-1 doi (NATIONALLICENCE)springer-10.1007/s10552-010-9688-1 Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: results from an Australian case-control study [Elektronische Daten] [Elizabeth Milne, Jill Royle, Lisa Bennett, Nicholas de Klerk, Helen Bailey, Carol Bower, Margaret Miller, John Attia, Rodney Scott, Maria Kirby, Bruce Armstrong] Objectives: To investigate whether maternal coffee and/or tea consumption during the last 6months of pregnancy was associated with risk of childhood ALL. Methods: Data on coffee and tea drinking during pregnancy from 337 case mothers and 697 control mothers were analyzed using unconditional multivariable logistic regression. A meta-analysis of our findings with those of previous studies was also conducted. Results: There was little evidence of an overall association between maternal coffee consumption and risk of ALL: OR 0.89 (95% CI 0.61, 1.30), although there was some suggestion that higher levels of intake might increase the risk in children of non-smoking mothers: OR for 2+ cups/day=1.44 (95% CI 0.85, 2.42); this was supported by our meta-analysis. Risk was also elevated among cases with chromosomal translocations. The overall OR for maternal tea consumption was 0.82 (95% CI 0.56, 1.18), although the OR for T-cell ALL was 0.21 (95% CI 0.08, 0.51). Among ALL cases with translocations, the ORs for tea consumption tended to be elevated: OR=1.70 (95% CI 0.79-3.68) for 2+ cups/day. Conclusions: The observed increased risk associated with coffee and tea consumption may be confined to ALL with translocations. These associations should be explored further in large international consortia. Springer Science+Business Media B.V., 2010 Child nationallicence Coffee nationallicence Diet nationallicence Leukemia nationallicence Tea nationallicence Milne Elizabeth Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut Royle Jill Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut Bennett Lisa Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut de Klerk Nicholas Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut Bailey Helen Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut Bower Carol Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut Miller Margaret Nutrition and Dietetics Program, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia aut Attia John Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Newcastle, NSW, Australia aut Scott Rodney Hunter Medical Research Institute, The School of Biomedical Sciences, Faculty of Health, University of Newcastle and the Hunter Area Pathology Service, HNEHealth, 2305, Newcastle, NSW, Australia aut Kirby Maria Women's and Children's Hospital, Adelaide, SA, Australia aut Armstrong Bruce Sydney School of Public Health, The University of Sydney, NSW, Australia aut Cancer Causes & Control Springer Netherlands 22/2(2011-02-01), 207-218 0957-5243 22:2<207 2011 22 10552 https://doi.org/10.1007/s10552-010-9688-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-010-9688-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Milne Elizabeth Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut NATIONALLICENCE 700 1- Royle Jill Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut NATIONALLICENCE 700 1- Bennett Lisa Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut NATIONALLICENCE 700 1- de Klerk Nicholas Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut NATIONALLICENCE 700 1- Bailey Helen Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut NATIONALLICENCE 700 1- Bower Carol Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, PO Box 855, 6872, West Perth, WA, Australia aut NATIONALLICENCE 700 1- Miller Margaret Nutrition and Dietetics Program, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia aut NATIONALLICENCE 700 1- Attia John Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Newcastle, NSW, Australia aut NATIONALLICENCE 700 1- Scott Rodney Hunter Medical Research Institute, The School of Biomedical Sciences, Faculty of Health, University of Newcastle and the Hunter Area Pathology Service, HNEHealth, 2305, Newcastle, NSW, Australia aut NATIONALLICENCE 700 1- Kirby Maria Women's and Children's Hospital, Adelaide, SA, Australia aut NATIONALLICENCE 700 1- Armstrong Bruce Sydney School of Public Health, The University of Sydney, NSW, Australia aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/2(2011-02-01), 207-218 0957-5243 22:2<207 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer