caa a22 4500 445316101 CHVBK 20180317142647.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10552-010-9696-1 doi (NATIONALLICENCE)springer-10.1007/s10552-010-9696-1 Fruit and vegetable intake and risk of cancer in the Swedish women's lifestyle and health cohort [Elektronische Daten] [Marie Löf, Sven Sandin, Pagona Lagiou, Dimitrios Trichopoulos, Hans-Olov Adami, Elisabete Weiderpass] Objective: To investigate whether intake of fruits and vegetables is associated with overall cancer incidence in a large prospective cohort of women in Sweden characterised by young age at enrolment (30-49years) and relatively low intake of fruits and vegetables. Methods: We followed prospectively 49,261 women, who completed a food frequency questionnaire in 1991-1992. A total of 2,347 incident invasive cancer cases were identified until December 2006. The occurrence of cancer was analysed by fitting Poisson regression models, estimating incidence rate ratios (RR) and 95% confidence intervals (CI). Results: The median intake of fruits and vegetables was 204g/day (10th; 90th percentile: 37; 564g/day). Intake of fruits and vegetables was not statistically significantly associated with overall cancer incidence. When we compared women in the highest quintile of fruit and vegetable intake to women in the lowest quintile, the RR for overall cancer was 1.01 (95% CI: 0.88-1.16). Similar results were obtained when investigating the effect of intake of fruits and vegetables separately and when we stratified women by age at follow-up. Conclusion: Fruit and vegetable intake was not associated with risk of total cancer in this prospective cohort of women in Sweden. The Author(s), 2010 Fruits and vegetables nationallicence Cancer nationallicence Cohort nationallicence Epidemiology nationallicence Löf Marie Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut Sandin Sven Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut Lagiou Pagona Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75M Asias Street, Goudi, 115 27, Athens, Greece aut Trichopoulos Dimitrios Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut Adami Hans-Olov Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut Weiderpass Elisabete Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut Cancer Causes & Control Springer Netherlands 22/2(2011-02-01), 283-289 0957-5243 22:2<283 2011 22 10552 https://doi.org/10.1007/s10552-010-9696-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-010-9696-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Löf Marie Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut NATIONALLICENCE 700 1- Sandin Sven Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut NATIONALLICENCE 700 1- Lagiou Pagona Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75M Asias Street, Goudi, 115 27, Athens, Greece aut NATIONALLICENCE 700 1- Trichopoulos Dimitrios Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut NATIONALLICENCE 700 1- Adami Hans-Olov Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut NATIONALLICENCE 700 1- Weiderpass Elisabete Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO 281, 171 77, Stockholm, Sweden aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/2(2011-02-01), 283-289 0957-5243 22:2<283 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer