caa a22 4500 445316152 CHVBK 20180317142648.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1007/s10552-011-9834-4 doi (NATIONALLICENCE)springer-10.1007/s10552-011-9834-4 Parental occupational exposure to exhausts, solvents, glues and paints, and risk of childhood leukemia [Elektronische Daten] [Alison Reid, Deborah Glass, Helen Bailey, Elizabeth Milne, Bruce Armstrong, Frank Alvaro, Lin Fritschi] Purpose: It is unknown whether parental occupational exposure to chemicals before during and after pregnancy increases the risk of acute lymphoblastic leukemia (ALL) in the offspring. Few studies on this topic have assessed maternal exposures. Methods: In an Australian case-control study of ALL in children aged <15 years, parents were asked about tasks they undertook in each job using a set of job-specific modules (JSMs). An expert reviewed the likelihood of exposure to exhausts, solvents, glues, and paints. Exposure was examined in each job 2years, 1year and anytime before birth of the child, and up to 1year after birth of child. Results: Solvent exposure was similar for case and control mothers in all time periods. More case mothers had moderate/high exposure to exhausts than control mothers anytime before the birth of the child (p=0.010). Exposure to moderate or substantial levels of exhausts by mothers (OR=1.97 95% CI 0.99-3.90) or fathers (OR=1.37 95% CI 1.01-1.86) before the birth increased the risk of ALL in their offspring. Exposure to paints, pigments, glues, and resins was similar in case and control parents. Conclusion: We found little evidence that parental occupational exposure to solvents, glues, and paints was associated with childhood ALL. There was some evidence ALL was associated with exhaust exposure. Springer Science+Business Media B.V., 2011 Childhood leukemia nationallicence Exhausts nationallicence Solvents nationallicence Parental occupational exposure nationallicence Reid Alison Western Australian Institute for Medical Research, M519, The University of Western Australia, 35 Stirling Highway, 6009, Crawley, WA, Australia aut Glass Deborah Monash Centre for Occupational and Environmental Epidemiology, Monash University, Melbourne, Australia aut Bailey Helen Telethon Institute for Child Health Research, University of Western Australia, Perth, Australia aut Milne Elizabeth Telethon Institute for Child Health Research, University of Western Australia, Perth, Australia aut Armstrong Bruce Sydney School of Public Health, University of Sydney, Sydney, Australia aut Alvaro Frank Department of Oncology, John Hunter Children's Hospital, New Lambton, NSW, Australia aut Fritschi Lin Western Australian Institute for Medical Research, M519, The University of Western Australia, 35 Stirling Highway, 6009, Crawley, WA, Australia aut Cancer Causes & Control Springer Netherlands 22/11(2011-11-01), 1575-1585 0957-5243 22:11<1575 2011 22 10552 https://doi.org/10.1007/s10552-011-9834-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10552-011-9834-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Reid Alison Western Australian Institute for Medical Research, M519, The University of Western Australia, 35 Stirling Highway, 6009, Crawley, WA, Australia aut NATIONALLICENCE 700 1- Glass Deborah Monash Centre for Occupational and Environmental Epidemiology, Monash University, Melbourne, Australia aut NATIONALLICENCE 700 1- Bailey Helen Telethon Institute for Child Health Research, University of Western Australia, Perth, Australia aut NATIONALLICENCE 700 1- Milne Elizabeth Telethon Institute for Child Health Research, University of Western Australia, Perth, Australia aut NATIONALLICENCE 700 1- Armstrong Bruce Sydney School of Public Health, University of Sydney, Sydney, Australia aut NATIONALLICENCE 700 1- Alvaro Frank Department of Oncology, John Hunter Children's Hospital, New Lambton, NSW, Australia aut NATIONALLICENCE 700 1- Fritschi Lin Western Australian Institute for Medical Research, M519, The University of Western Australia, 35 Stirling Highway, 6009, Crawley, WA, Australia aut NATIONALLICENCE 773 0- Cancer Causes & Control Springer Netherlands 22/11(2011-11-01), 1575-1585 0957-5243 22:11<1575 2011 22 10552 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer