caa a22 4500 445318074 CHVBK 20180317142654.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10126-010-9294-y doi (NATIONALLICENCE)springer-10.1007/s10126-010-9294-y Pettit Robin Department of Chemistry and Biochemistry, Arizona State University, 85287-2404, Tempe, AZ, USA aut Culturability and Secondary Metabolite Diversity of Extreme Microbes: Expanding Contribution of Deep Sea and Deep-Sea Vent Microbes to Natural Product Discovery [Elektronische Daten] [Robin Pettit] Microbes from extreme environments do not necessarily require extreme culture conditions. Perhaps the most extreme environments known, deep-sea hydrothermal vent sites, support an incredible array of archaea, bacteria, and fungi, many of which have now been cultured. Microbes cultured from extreme environments have not disappointed in the natural products arena; diverse bioactive secondary metabolites have been isolated from cultured extreme-tolerant microbes, extremophiles, and deep-sea microbes. The contribution of vent microbes to our arsenal of natural products will likely grow, given the culturability of vent microbes; their metabolic, physiologic, and phylogenetic diversity; numerous reports of bioactive natural products from microbes inhabiting high acid, high temperature, or high pressure environments; and the recent isolation of new chroman derivatives and siderophores from deep-sea hydrothermal vent bacteria. Springer Science+Business Media, LLC, 2010 Deep-sea hydrothermal vent nationallicence Extremophile nationallicence Natural product nationallicence Secondary metabolite nationallicence Marine Biotechnology Springer-Verlag 13/1(2011-02-01), 1-11 1436-2228 13:1<1 2011 13 10126 https://doi.org/10.1007/s10126-010-9294-y text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10126-010-9294-y text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Pettit Robin Department of Chemistry and Biochemistry, Arizona State University, 85287-2404, Tempe, AZ, USA aut NATIONALLICENCE 773 0- Marine Biotechnology Springer-Verlag 13/1(2011-02-01), 1-11 1436-2228 13:1<1 2011 13 10126 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer