caa a22 4500 445318481 CHVBK 20180317142655.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s10126-010-9292-0 doi (NATIONALLICENCE)springer-10.1007/s10126-010-9292-0 Uncovering the Mechanisms of Shrimp Innate Immune Response by RNA Interference [Elektronische Daten] [Ikuo Hirono, Fernand Fagutao, Hidehiro Kondo, Takashi Aoki] Because of the importance of shrimp in world aquaculture, there is much interest in understanding their immune system in order to improve their resistance to pathogenic microorganisms. An effective tool in studying genes involved in the immune response in shrimp is RNA interference (RNAi). RNAi, first recognized as an antiviral response against RNA viruses, is a cellular mechanism that is triggered by double-stranded RNAs and results in the degradation of homologous genes. In this review, we describe the current studies of genes in shrimp that employed RNAi technology to elucidate or confirm their functions. We also review the potential of RNAi to elicit antiviral response in shrimp. Springer Science+Business Media, LLC, 2010 Shrimp nationallicence RNAi nationallicence Innate immunity nationallicence Hirono Ikuo Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, 108-8477, Tokyo, Japan aut Fagutao Fernand Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, 108-8477, Tokyo, Japan aut Kondo Hidehiro Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, 108-8477, Tokyo, Japan aut Aoki Takashi Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, 108-8477, Tokyo, Japan aut Marine Biotechnology Springer-Verlag 13/4(2011-08-01), 622-628 1436-2228 13:4<622 2011 13 10126 https://doi.org/10.1007/s10126-010-9292-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10126-010-9292-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hirono Ikuo Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, 108-8477, Tokyo, Japan aut NATIONALLICENCE 700 1- Fagutao Fernand Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, 108-8477, Tokyo, Japan aut NATIONALLICENCE 700 1- Kondo Hidehiro Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, 108-8477, Tokyo, Japan aut NATIONALLICENCE 700 1- Aoki Takashi Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, 108-8477, Tokyo, Japan aut NATIONALLICENCE 773 0- Marine Biotechnology Springer-Verlag 13/4(2011-08-01), 622-628 1436-2228 13:4<622 2011 13 10126 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer