caa a22 4500 445321512 CHVBK 20180317142705.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10534-011-9437-2 doi (NATIONALLICENCE)springer-10.1007/s10534-011-9437-2 Power plays: iron transport and energy transduction in pathogenic vibrios [Elektronische Daten] [Ryan Kustusch, Carole Kuehl, Jorge Crosa] The Vibrios are a unique group of bacteria inhabiting a vast array of aquatic environments. Many Vibrio species are capable of infecting a wide assortment of hosts. Some of these species include V. parahaemolyticus, V. alginolyticus, V. vulnificus, V. anguillarum, and V. cholerae. The ability of these organisms to utilize iron is essential in establishing both an infection in their hosts as well as surviving in the environment. Bacteria are able to sequester iron through the secretion of low molecular weight iron chelators termed siderophores. The iron-siderophore complexes are bound by specific outer membrane receptors and are brought through both the outer and inner membranes of the cell. The energy needed to drive this active transport is achieved through the TonB energy transduction system. When first elucidated in E. coli, the TonB system was shown to be a three protein complex consisting of TonB, ExbB and ExbD. Most Vibrio species carry two TonB systems. The second TonB system includes a fourth protein; TtpC, which is essential for TonB2 mediated iron transport. Some Vibrio species have been shown to carry a third TonB system that also includes a TtpC protein. Springer Science+Business Media, LLC., 2011 Vibrio nationallicence Iron nationallicence TonB nationallicence TtpC nationallicence Kustusch Ryan Department of Molecular Microbiology and Immunology, Oregon Health Science University, Mail Code L220, 3181 S.W. Sam Jackson Park Road, 97201-3098, Portland, OR, USA aut Kuehl Carole Department of Molecular Microbiology and Immunology, Oregon Health Science University, Mail Code L220, 3181 S.W. Sam Jackson Park Road, 97201-3098, Portland, OR, USA aut Crosa Jorge Department of Molecular Microbiology and Immunology, Oregon Health Science University, Mail Code L220, 3181 S.W. Sam Jackson Park Road, 97201-3098, Portland, OR, USA aut BioMetals Springer Netherlands 24/3(2011-06-01), 559-566 0966-0844 24:3<559 2011 24 10534 https://doi.org/10.1007/s10534-011-9437-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10534-011-9437-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kustusch Ryan Department of Molecular Microbiology and Immunology, Oregon Health Science University, Mail Code L220, 3181 S.W. Sam Jackson Park Road, 97201-3098, Portland, OR, USA aut NATIONALLICENCE 700 1- Kuehl Carole Department of Molecular Microbiology and Immunology, Oregon Health Science University, Mail Code L220, 3181 S.W. Sam Jackson Park Road, 97201-3098, Portland, OR, USA aut NATIONALLICENCE 700 1- Crosa Jorge Department of Molecular Microbiology and Immunology, Oregon Health Science University, Mail Code L220, 3181 S.W. Sam Jackson Park Road, 97201-3098, Portland, OR, USA aut NATIONALLICENCE 773 0- BioMetals Springer Netherlands 24/3(2011-06-01), 559-566 0966-0844 24:3<559 2011 24 10534 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer