caa a22 4500 445327944 CHVBK 20180317142727.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10953-011-9767-2 doi (NATIONALLICENCE)springer-10.1007/s10953-011-9767-2 Solubility of Acetaminophen and Ibuprofen in Polyethylene Glycol 600, N-Methyl Pyrrolidone and Water Mixtures [Elektronische Daten] [Shahla Soltanpour, Abolghasem Jouyban] The solubility of acetaminophen and ibuprofen in binary and ternary mixtures of N-methyl pyrrolidone, polyethylene glycol 600 and water at 25 °C were determined and the solubilities are mathematically represented by the Jouyban-Acree model. The density of the solute-free solvent mixtures was measured and employed to train the Jouyban-Acree model and then the densities of the saturated solutions were predicted. The overall mean relative deviations (OMRDs) for fitting the solubility data of acetaminophen and ibuprofen in binary mixtures are 3.2% and 6.0%, respectively. The OMRDs for fitting the solubilities in ternary solvent mixtures for acetaminophen and ibuprofen are 15.0% and 28.6%, respectively, and the OMRD values for predicting all solubilities of acetaminophen and ibuprofen by a trained version of the Jouyban-Acree model are 9.4% and 17.8%, respectively. The prediction OMRD for the density of saturated solutions is 1.9%. Springer Science+Business Media, LLC, 2011 Jouyban-Acree model nationallicence Acetaminophen nationallicence Ibuprofen nationallicence Solubility nationallicence N-methyl pyrrolidone nationallicence Soltanpour Shahla Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, 51664, Tabriz, Iran aut Jouyban Abolghasem Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, 51664, Tabriz, Iran aut Journal of Solution Chemistry Springer US; http://www.springer-ny.com 40/12(2011-12-01), 2032-2045 0095-9782 40:12<2032 2011 40 10953 https://doi.org/10.1007/s10953-011-9767-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10953-011-9767-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Soltanpour Shahla Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, 51664, Tabriz, Iran aut NATIONALLICENCE 700 1- Jouyban Abolghasem Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, 51664, Tabriz, Iran aut NATIONALLICENCE 773 0- Journal of Solution Chemistry Springer US; http://www.springer-ny.com 40/12(2011-12-01), 2032-2045 0095-9782 40:12<2032 2011 40 10953 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer