caa a22 4500 445327979 CHVBK 20180317142727.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s10953-011-9768-1 doi (NATIONALLICENCE)springer-10.1007/s10953-011-9768-1 Complex Formation Between Ferric(III), Chromium(III), and Cupric(II) Metal Ions and (O,N) and (O,O) Donor Ligands with Biological Relevance in Aqueous Solution [Elektronische Daten] [Ahmed Fazary, Erzalina Hernowo, Artik Angkawijaya, Tse-Chuan Chou, Chih Lin, Mohamed Taha, Yi-Hsu Ju] The complexation equilibria of L-norleucine and gallic acid were studied in aqueous solutions at 25.00 °C and ionic strength 0.15 mol⋅dm−3 (NaNO3), by means of potentiometry and spectrophotometry. The ferric (FeIII), chromium (CrIII), and cupric (CuII) complexing abilities of L-norleucine and gallic acid, along with their overall stability constants, were obtained with the HYPERQUAD 2008 program from the potentiometric data. The concentration distributions of the various complex species in solution were evaluated and discussed. UV-visible spectroscopic measurements were carried out to give qualitative information about the composition of the complexes formed in these solutions. The cytotoxic activities of the binary and ternary metal complexes of L-norleucine and gallic acid were tested and evaluated against HEp-2 (human laryngeal carcinoma), Daoy (human medulloblastoma), MCF-7 (human breast adenocarcinoma), and WiDr (human colon adenocarcinoma) tumor cell lines. Also, their antioxidant activities were examined by free radical scavenging assay. Springer Science+Business Media, LLC, 2011 Stability constants nationallicence L-Norleucine nationallicence Gallic acid nationallicence Potentiometry nationallicence Spectroscopy nationallicence Cytotoxic nationallicence Antioxidant nationallicence Fazary Ahmed Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut Hernowo Erzalina Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut Angkawijaya Artik Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut Chou Tse-Chuan School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Rd. Sec. 1, 100, Taipei, Taiwan aut Lin Chih School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Rd. Sec. 1, 100, Taipei, Taiwan aut Taha Mohamed Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut Ju Yi-Hsu Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut Journal of Solution Chemistry Springer US; http://www.springer-ny.com 40/12(2011-12-01), 1965-1986 0095-9782 40:12<1965 2011 40 10953 https://doi.org/10.1007/s10953-011-9768-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10953-011-9768-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fazary Ahmed Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut NATIONALLICENCE 700 1- Hernowo Erzalina Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut NATIONALLICENCE 700 1- Angkawijaya Artik Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut NATIONALLICENCE 700 1- Chou Tse-Chuan School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Rd. Sec. 1, 100, Taipei, Taiwan aut NATIONALLICENCE 700 1- Lin Chih School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Rd. Sec. 1, 100, Taipei, Taiwan aut NATIONALLICENCE 700 1- Taha Mohamed Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut NATIONALLICENCE 700 1- Ju Yi-Hsu Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, 106-07, Taipei, Taiwan aut NATIONALLICENCE 773 0- Journal of Solution Chemistry Springer US; http://www.springer-ny.com 40/12(2011-12-01), 1965-1986 0095-9782 40:12<1965 2011 40 10953 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer