caa a22 4500 445328061 CHVBK 20180317142727.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s10953-011-9655-9 doi (NATIONALLICENCE)springer-10.1007/s10953-011-9655-9 Ruthenium(III) Catalyzed Oxidative Degradation ofAmitriptyline-A Tricyclic Antidepressant Drug byPermanganate inAqueous Acidic Medium [Elektronische Daten] [Jyothi Abbar, Shekappa Lamani, Sharanappa Nandibewoor] The oxidation of amitriptyline by potassium permanganate has been investigated spectrophotometrically in the presence of ruthenium(III) as catalyst in aqueous acidic medium at a constant ionic strength of 0.20mol⋅dm−3. The stoichiometry was found to be 1:1 in terms of the mole ratio of amitriptyline and permanganate ions consumed. The order of the reaction with respect to manganese(VII) and ruthenium(III) concentration was unity while the order with respect to amitriptyline was less than unity over the concentration range studied. The rate increased with an increase in acid concentration. The reaction rates revealed that the Ru(III) catalyzed reaction was about eight-fold faster than the uncatalyzed reaction. The oxidation products were identified by spectral analysis. A tentative mechanism consistent with the kinetics has been proposed. The reaction constants involved in the different steps of the reaction mechanism were calculated. Kinetic experiments suggest that HMnO4 is the reactive permanganate species and [Ru(H2O)6]3+ is the reactive Ru(III) species. Springer Science+Business Media, LLC, 2011 Amitriptyline nationallicence Permanganate nationallicence Ruthenium(III) nationallicence Oxidation nationallicence Kinetics nationallicence Mechanism nationallicence Abbar Jyothi P.G. Department of Studies in Chemistry, Karnatak University, 580003, Dharwad, India aut Lamani Shekappa P.G. Department of Studies in Chemistry, Karnatak University, 580003, Dharwad, India aut Nandibewoor Sharanappa P.G. Department of Studies in Chemistry, Karnatak University, 580003, Dharwad, India aut Journal of Solution Chemistry Springer US; http://www.springer-ny.com 40/3(2011-03-01), 502-520 0095-9782 40:3<502 2011 40 10953 https://doi.org/10.1007/s10953-011-9655-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10953-011-9655-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Abbar Jyothi P.G. Department of Studies in Chemistry, Karnatak University, 580003, Dharwad, India aut NATIONALLICENCE 700 1- Lamani Shekappa P.G. Department of Studies in Chemistry, Karnatak University, 580003, Dharwad, India aut NATIONALLICENCE 700 1- Nandibewoor Sharanappa P.G. Department of Studies in Chemistry, Karnatak University, 580003, Dharwad, India aut NATIONALLICENCE 773 0- Journal of Solution Chemistry Springer US; http://www.springer-ny.com 40/3(2011-03-01), 502-520 0095-9782 40:3<502 2011 40 10953 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer