caa a22 4500 445328649 CHVBK 20180317142730.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s10953-011-9692-4 doi (NATIONALLICENCE)springer-10.1007/s10953-011-9692-4 Spectroscopic Analysis of the Interactions of Anthraquinone Derivatives (Alizarin, Alizarin-DA and Alizarin-DA-Fe) with Bovine Serum Albumin (BSA) [Elektronische Daten] [Jingqun Gao, Yuwei Guo, Jun Wang, Xudong Jin, Zhiqiu Wang, Tingting Fan, Kai Li, Yongnan Xu] In this paper, three anthraquinones (alizarin (1,2-dihydroxy-9,10-anthraquinone), alizarin-DA (1,2-dihydroxy-9,10-anthraquinone-3-aminomethyl-N,N-diacetic acid) and alizarin-DA-Fe (1,2-dihydroxy-9,10-anthraquinone-3-aminomethyl-N,N-diacetate-ferric(III))) with a tricyclic anthraquinone planar structure are used as quenchers, to study their interaction with bovine serum albumin (BSA) molecules by fluorescence spectroscopy. The results show that these three anthraquinones can bind to BSA molecules efficiently but the stabilities decrease in the order alizarin, alizarin-DA and alizarin-DA-Fe. In addition, synchronous fluorescence spectroscopy indicates that the tryptophan (Trp) residues of BSA molecules are more accessible to alizarin and alizarin-DA than the tyrosine (Tyr) residues, but both have similar accessibility to alizarin-DA-Fe. Springer Science+Business Media, LLC, 2011 Interaction nationallicence Bovine serum albumin (BSA) nationallicence Anthraquinone derivatives nationallicence Fluorescence spectroscopy nationallicence Gao Jingqun Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut Guo Yuwei Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut Wang Jun Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut Jin Xudong Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut Wang Zhiqiu Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut Fan Tingting Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut Li Kai Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut Xu Yongnan Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut Journal of Solution Chemistry Springer US; http://www.springer-ny.com 40/5(2011-05-01), 876-888 0095-9782 40:5<876 2011 40 10953 https://doi.org/10.1007/s10953-011-9692-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10953-011-9692-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gao Jingqun Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut NATIONALLICENCE 700 1- Guo Yuwei Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut NATIONALLICENCE 700 1- Wang Jun Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut NATIONALLICENCE 700 1- Jin Xudong Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut NATIONALLICENCE 700 1- Wang Zhiqiu Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut NATIONALLICENCE 700 1- Fan Tingting Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut NATIONALLICENCE 700 1- Li Kai Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut NATIONALLICENCE 700 1- Xu Yongnan Department of Chemistry, Liaoning University, 110036, Shenyang, P.R. China aut NATIONALLICENCE 773 0- Journal of Solution Chemistry Springer US; http://www.springer-ny.com 40/5(2011-05-01), 876-888 0095-9782 40:5<876 2011 40 10953 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer