caa a22 4500 445328983 CHVBK 20180317142731.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s10143-010-0286-1 doi (NATIONALLICENCE)springer-10.1007/s10143-010-0286-1 Combined craniofacial resection of anterior skull base tumors: long-term results and experience of single institution [Elektronische Daten] [Bashar Abuzayed, Bulent Canbaz, Galip Sanus, Seckin Aydin, Harun Cansiz] In this article, the authors are presenting their experience and the results with combined craniofacial resection of anterior skull base tumors based on a review of 27 constitutive cases. Our data are evaluated in comparison to other major centers in other parts of the world, and possible factors that might influence surgical outcome and survival are discussed. Twenty-seven patients diagnosed with anterior skull base tumors between 1999 and 2009 were treated by combined craniofacial resection. Of these patients, there were 19 males (70, 3%) and eight females (29, 7%). The age ranged between 11 and 75years (mean = 45.9 ± 17.6years). The follow-up period ranged between 14 and 123months (avarage = 74months). The most common presenting symptoms were nasal obstruction and vision disturbance (11 patients for each −40.7%). Total resection was achieved in 24 patients (89%), while subtotal resection was done in three patients (11%). The most common complication was CSF fistule with rhinorrhea, which occurred in five patients (18.5%). Eight patients had recurrences at the time of this long-term follow-up. There were two mortalities in the early postoperative period and seven deaths in the long-term follow-up (overall mortality, 33.3%). The overall 5-year overall survival for all patients in our series was 70.4%. The 5-year overall survival was 62% for patients with malignant tumors and 100% for patients with benign tumors. Combined craniofacial resection of tumors of the anterior skull base is an effective approach for the management of these pathologies. The effectiveness is clearly demonstrated by the clinical results and outcomes of these patients' groups. The favorable prognosis is enhanced by significantly by total resection with negative tumor margins. Springer-Verlag, 2010 Anterior skull base tumor nationallicence Combined craniofacial approach nationallicence Skull base nationallicence Surgical treatment nationallicence Abuzayed Bashar Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Street, K.M. Pasa, Fatih, PO Box: 34089, Istanbul, Turkey aut Canbaz Bulent Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Street, K.M. Pasa, Fatih, PO Box: 34089, Istanbul, Turkey aut Sanus Galip Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Street, K.M. Pasa, Fatih, PO Box: 34089, Istanbul, Turkey aut Aydin Seckin Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Street, K.M. Pasa, Fatih, PO Box: 34089, Istanbul, Turkey aut Cansiz Harun Department of Otorhinolaryngology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey aut Neurosurgical Review Springer-Verlag 34/1(2011-01-01), 101-113 0344-5607 34:1<101 2011 34 10143 https://doi.org/10.1007/s10143-010-0286-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10143-010-0286-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Abuzayed Bashar Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Street, K.M. Pasa, Fatih, PO Box: 34089, Istanbul, Turkey aut NATIONALLICENCE 700 1- Canbaz Bulent Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Street, K.M. Pasa, Fatih, PO Box: 34089, Istanbul, Turkey aut NATIONALLICENCE 700 1- Sanus Galip Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Street, K.M. Pasa, Fatih, PO Box: 34089, Istanbul, Turkey aut NATIONALLICENCE 700 1- Aydin Seckin Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Street, K.M. Pasa, Fatih, PO Box: 34089, Istanbul, Turkey aut NATIONALLICENCE 700 1- Cansiz Harun Department of Otorhinolaryngology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey aut NATIONALLICENCE 773 0- Neurosurgical Review Springer-Verlag 34/1(2011-01-01), 101-113 0344-5607 34:1<101 2011 34 10143 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer