caa a22 4500 445328991 CHVBK 20180317142731.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s10143-010-0294-1 doi (NATIONALLICENCE)springer-10.1007/s10143-010-0294-1 Recanalization therapy for acute ischemic stroke, part 2: mechanical intra-arterial technologies [Elektronische Daten] [Saeed Ansari, Maryam Rahman, Douglas McConnell, Michael Waters, Brian Hoh, J. Mocco] Stroke therapy has been revolutionized in the past two decades with the widespread implementation of chemical thrombolysis for acute stroke. However, chemical thrombolysis continues to be limited in its efficacy secondary to relatively short time windows and a high associated risk of hemorrhage. In an attempt to minimize hemorrhagic complications and extend the available therapeutic window, mechanical devices designed specifically for thrombus removal, clot obliteration, and arterial revascularization have experienced a recent surge in development and utilization. As such, chemical thrombolytics now represent only one of many options in acute stroke therapy. These new mechanical devices have extended the potential treatment window and now provide alternatives to patients who do not respond to conventional intravenous thrombolysis. This review will discuss the development of these devices, supporting literature, and the individual strengths that each engenders towards a life-saving therapy for stroke. Springer-Verlag, 2010 Mechanical instrument nationallicence Stroke nationallicence Thrombolysis nationallicence Stents nationallicence Review nationallicence Ansari Saeed Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut Rahman Maryam Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut McConnell Douglas Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut Waters Michael Department of Neurology, University of Florida, Gainesville, FL, USA aut Hoh Brian Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut Mocco J. Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut Neurosurgical Review Springer-Verlag 34/1(2011-01-01), 11-20 0344-5607 34:1<11 2011 34 10143 https://doi.org/10.1007/s10143-010-0294-1 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10143-010-0294-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ansari Saeed Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Rahman Maryam Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- McConnell Douglas Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Waters Michael Department of Neurology, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Hoh Brian Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Mocco J. Department of Neurosurgery, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 773 0- Neurosurgical Review Springer-Verlag 34/1(2011-01-01), 11-20 0344-5607 34:1<11 2011 34 10143 Metadata rights reserved Springer special CC-BY-NC licence nationallicence SWISSBIB 445328975 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer