caa a22 4500 445329173 CHVBK 20180317142731.0 cr unu---uuuuu 170323e20110701xx s 000 0 eng 10.1007/s10143-011-0324-7 doi (NATIONALLICENCE)springer-10.1007/s10143-011-0324-7 Intratumoural hydrogen peroxide injection during resection of metastatic vertebral melanoma. Technical note [Elektronische Daten] [Luciano Mastronardi, Luc DeWaele] It is well recognized that the surgical removal of vertebral metastases of several malignant tumours often causes extensive bleeding, increasing the difficulties for surgeons and the risks for patients. Among the different subtypes of malignancies involved, melanoma has an extensive vascularity, and its resection is frequently challenging because of a continuous and annoying bleeding. A 55-year-old patient with a history of treated melanoma was operated on urgently for a severe T10-11 spinal cord compression by a huge metastasis involving the peridural space and the vertebral bone. During the resection, we injected, in successive stages, a total of 5ml of 3% hydrogen peroxide (H2O2) solution, with good control of tumour bleeding. The patient had no problems related to the procedure, and 6months after the surgery he is able to perform sustained walking. The aim of this manuscript is to report a safe, simple, effective, inexpensive and readily available technique for intraoperative haemostasis that could allow the control of tumour bleeding and facilitate its excision. Springer-Verlag, 2011 Hydrogen peroxide nationallicence Haemostasis nationallicence Melanoma nationallicence Vertebral metastasis nationallicence Intratumoral injection nationallicence Mastronardi Luciano Department of Neurosurgery, San Filippo Neri Hospital, Rome, Italy aut DeWaele Luc Department of Neurosurgery, Sint-Lucas Hospital, Ghent, Belgium aut Neurosurgical Review Springer-Verlag 34/3(2011-07-01), 389-391 0344-5607 34:3<389 2011 34 10143 https://doi.org/10.1007/s10143-011-0324-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10143-011-0324-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mastronardi Luciano Department of Neurosurgery, San Filippo Neri Hospital, Rome, Italy aut NATIONALLICENCE 700 1- DeWaele Luc Department of Neurosurgery, Sint-Lucas Hospital, Ghent, Belgium aut NATIONALLICENCE 773 0- Neurosurgical Review Springer-Verlag 34/3(2011-07-01), 389-391 0344-5607 34:3<389 2011 34 10143 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer