caa a22 4500 445329262 CHVBK 20180317142732.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10143-011-0316-7 doi (NATIONALLICENCE)springer-10.1007/s10143-011-0316-7 Natural history of idiopathic normal-pressure hydrocephalus [Elektronische Daten] [Ahmed Toma, Simon Stapleton, Marios Papadopoulos, Neil Kitchen, Laurence Watkins] Natural history of idiopathic normal-pressure hydrocephalus (INPH) is not clear. We performed a literature search for studies that looked into the outcome of unshunted INPH patients trying to answer the following questions: Do all INPH patients deteriorate without shunt? If yes, at what rate? Do some NPH patients improve without shunt? If yes, to what extent? Six studies objectively described the outcome of 102 INPH patients. Result shows that without surgery, most INPH patients had measurable deterioration as early as 3months following initial assessment. A small number of patients might improve without shunt, however the extent of improvement is not clear. The homogeneity of the findings of the cohort studies provided high evidence supporting the rule of shunt surgery in INPH patients. Springer-Verlag, 2011 Normal-pressure hydrocephalus nationallicence Chronic adult hydrocephalus nationallicence Natural history nationallicence Toma Ahmed Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK aut Stapleton Simon Academic Neurosurgery Unit, St George's University of London, London, UK aut Papadopoulos Marios Academic Neurosurgery Unit, St George's University of London, London, UK aut Kitchen Neil Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK aut Watkins Laurence Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK aut Neurosurgical Review Springer-Verlag 34/4(2011-10-01), 433-439 0344-5607 34:4<433 2011 34 10143 https://doi.org/10.1007/s10143-011-0316-7 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10143-011-0316-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Toma Ahmed Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK aut NATIONALLICENCE 700 1- Stapleton Simon Academic Neurosurgery Unit, St George's University of London, London, UK aut NATIONALLICENCE 700 1- Papadopoulos Marios Academic Neurosurgery Unit, St George's University of London, London, UK aut NATIONALLICENCE 700 1- Kitchen Neil Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK aut NATIONALLICENCE 700 1- Watkins Laurence Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK aut NATIONALLICENCE 773 0- Neurosurgical Review Springer-Verlag 34/4(2011-10-01), 433-439 0344-5607 34:4<433 2011 34 10143 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer