caa a22 4500 445329300 CHVBK 20180317142732.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10143-011-0329-2 doi (NATIONALLICENCE)springer-10.1007/s10143-011-0329-2 Endonasal endoscopic resection of esthesioneuroblastoma: the Johns Hopkins Hospital experience and review of the literature [Elektronische Daten] [Gary Gallia, Douglas Reh, Vafi Salmasi, Ari Blitz, Wayne Koch, Masaru Ishii] Esthesioneuroblastoma is an uncommon malignant tumor originating in the upper nasal cavity. The surgical treatment for this tumor has traditionally been via an open craniofacial resection. Over the past decade, there has been tremendous development in endoscopic techniques. In this report, we performed a retrospective analysis of patients with esthesioneuroblastomas treated with a purely endonasal endoscopic approach and resection at the Johns Hopkins Hospital between January 2005 and April 2010. A total of eight patients with esthesioneuroblastoma, five men and three women, were identified. Six patients were treated for primary disease, and two were treated for tumor recurrence. The modified Kadish staging was A in one patient (12.5%), B in two patients (25%), C in four patients (50%), and D in one patient (12.5%). All patients had a complete resection with negative intraoperative margins. One patient had intraoperative hypertension; there were no perioperative complications. With a mean follow-up of over 27months, all patients are without evidence of disease. In addition, we reviewed the literature and identified several overlapping case series of patients with esthesioneuroblastoma treated via a purely endoscopic technique. Our series adds to the growing experience of expanded endonasal endoscopic surgery in the treatment of skull base tumors including esthesioneuroblastoma. Longer follow-up on a larger number of patients is required to further demonstrate the utility of endoscopic approaches in the management of this malignancy. Springer-Verlag, 2011 Esthesioneuroblastoma nationallicence Olfactory neuroblastoma nationallicence Expanded endonasal approach nationallicence Endoscopy nationallicence Endoscopic nationallicence Skull base nationallicence Gallia Gary Department of Neurosurgery, Johns Hopkins Hospital, 600 North Wolfe Street, Phipps Building, Room 118, 21287, Baltimore, MD, USA aut Reh Douglas Department of Otolaryngology, Johns Hopkins Hospital, 21287, Baltimore, MD, USA aut Salmasi Vafi Department of Neurosurgery, Johns Hopkins Hospital, 600 North Wolfe Street, Phipps Building, Room 118, 21287, Baltimore, MD, USA aut Blitz Ari Department of Radiology, Johns Hopkins Hospital, 21287, Baltimore, MD, USA aut Koch Wayne Department of Otolaryngology, Johns Hopkins Hospital, 21287, Baltimore, MD, USA aut Ishii Masaru Department of Otolaryngology, Johns Hopkins Hospital, 21287, Baltimore, MD, USA aut Neurosurgical Review Springer-Verlag 34/4(2011-10-01), 465-475 0344-5607 34:4<465 2011 34 10143 https://doi.org/10.1007/s10143-011-0329-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10143-011-0329-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gallia Gary Department of Neurosurgery, Johns Hopkins Hospital, 600 North Wolfe Street, Phipps Building, Room 118, 21287, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Reh Douglas Department of Otolaryngology, Johns Hopkins Hospital, 21287, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Salmasi Vafi Department of Neurosurgery, Johns Hopkins Hospital, 600 North Wolfe Street, Phipps Building, Room 118, 21287, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Blitz Ari Department of Radiology, Johns Hopkins Hospital, 21287, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Koch Wayne Department of Otolaryngology, Johns Hopkins Hospital, 21287, Baltimore, MD, USA aut NATIONALLICENCE 700 1- Ishii Masaru Department of Otolaryngology, Johns Hopkins Hospital, 21287, Baltimore, MD, USA aut NATIONALLICENCE 773 0- Neurosurgical Review Springer-Verlag 34/4(2011-10-01), 465-475 0344-5607 34:4<465 2011 34 10143 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer