caa a22 4500 445332778 CHVBK 20180317142742.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1245/s10434-010-1207-9 doi (NATIONALLICENCE)springer-10.1245/s10434-010-1207-9 Radiocolloid in Combination with Methylene Dye Localization, Rather Than Wire Localization, is a Preferred Procedure for Excisional Biopsy of Nonpalpable Breast Lesions [Elektronische Daten] [Jun Tang, Xiao-Ming Xie, Xi Wang, Ze-Ming Xie, Jie-Hua He, Yao-Pan Wu, Wei Fan, Jian-Hua Fu, Ming-Tian Yang] Background: Wire localization (WL) is traditionally performed before excisional biopsy for patients with nonpalpable breast lesions, but it has several disadvantages. Our current study examines whether the method of radiocolloid combined with methylene dye localization (RCML) has an advantage over WL. Materials and Methods: From August 2006 to May 2009, 157 patients with nonpalpable breast lesions classified as BI-RADS category 5 were enrolled in our study. Of the 157 patients, 78 were assigned to WL and 79 to RCML. The status of surgical margins, weight of specimens, length of incisions, and duration of operation were compared between these two groups. Results: All patients were diagnosed after first excisional biopsy. The patients with malignancy accounted for 55.1% in WL group, and 53.2% in RCML group. For malignant lesions, fewer patients undergoing RCML had close or involved surgical margins than did those who had WL (19.0% vs. 39.5%, P=.038). The mean weight of specimen was 45.2g in WL group and 39.0g in RCML group (P<.001). The mean length of incision was 44.8mm in WL group and 36.3mm in RCML group (P<.001). The mean time of operation was 16.3min for WL and 14.7min for RCML (P=.001). Conclusions: RCML provides precise identification of the site of the nonpalpable lesion and a visible marker to the lesion for surgeons and allows rapid, easy, and accurate excision of nonpalpable breast lesions. Therefore, RCML is a promising alternative to WL. Society of Surgical Oncology, 2010 Tang Jun State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut Xie Xiao-Ming State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut Wang Xi State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut Xie Ze-Ming State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut He Jie-Hua State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut Wu Yao-Pan State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut Fan Wei State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut Fu Jian-Hua State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut Yang Ming-Tian State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut Annals of Surgical Oncology Springer-Verlag 18/1(2011-01-01), 109-113 1068-9265 18:1<109 2011 18 10434 https://doi.org/10.1245/s10434-010-1207-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-010-1207-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tang Jun State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut NATIONALLICENCE 700 1- Xie Xiao-Ming State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut NATIONALLICENCE 700 1- Wang Xi State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut NATIONALLICENCE 700 1- Xie Ze-Ming State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut NATIONALLICENCE 700 1- He Jie-Hua State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut NATIONALLICENCE 700 1- Wu Yao-Pan State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut NATIONALLICENCE 700 1- Fan Wei State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut NATIONALLICENCE 700 1- Fu Jian-Hua State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut NATIONALLICENCE 700 1- Yang Ming-Tian State Key Laboratory of Oncology in South China, Sun Yat-sen University, Guangzhou, China aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/1(2011-01-01), 109-113 1068-9265 18:1<109 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer