caa a22 4500 445332972 CHVBK 20180317142743.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1245/s10434-010-1292-9 doi (NATIONALLICENCE)springer-10.1245/s10434-010-1292-9 Salvage Surgery for Neck Residue or Recurrence of Nasopharyngeal Carcinoma: A 10-Year Experience [Elektronische Daten] [Ling Zhang, Yong-xue Zhu, Yu Wang, Cai-ping Huang, Yi Wu, Qing-hai Ji] Background: To assess the outcome of and determine prognostic factors for neck residue or recurrence of nasopharyngeal carcinoma (NPC) in patients treated with a salvage neck dissection. Materials and Methods: Over a 10-year period (from January 1998 through December 2007) in a tertiary hospital, we systematically reviewed the clinical charts of 355 patients with NPC who were diagnosed with neck residue or recurrence of nasopharyngeal carcinoma, after radical definitive radiotherapy with or without chemotherapy. Results: The group with recurrent nodal disease consisted of 285 patients (80.3%), while the group with residual nodal disease included 70 patients (19.7%). There were no patients died of the surgery complications. Overall survival (OS), disease-free survival (DFS), and disease-specific survival (DSS) were 54.11, 35.01, and 55.59%, respectively, at 3-year, and 26.03, 22.65, and 27.84%, respectively, at 5-year. The local control rate in the neck was 70.92% at 3years and 60.98% at 5years. For all the 3 survival outcomes (OS, DFS, and DSS) and the local control rate of disease in the neck, there were significant differences between the "residue group” and "recurrence group.” Conclusions: Radical neck dissection is proven to be safe and effective in the treatment of the neck failure. Our study has demonstrated that it may be possible to choose the selective lymph node dissection for patients of the residue group. The Author(s), 2010 Zhang Ling Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut Zhu Yong-xue Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut Wang Yu Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut Huang Cai-ping Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut Wu Yi Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut Ji Qing-hai Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut Annals of Surgical Oncology Springer-Verlag 18/1(2011-01-01), 233-238 1068-9265 18:1<233 2011 18 10434 https://doi.org/10.1245/s10434-010-1292-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-010-1292-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zhang Ling Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Zhu Yong-xue Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Wang Yu Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Huang Cai-ping Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Wu Yi Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Ji Qing-hai Department of Head and Neck Surgery, Fudan University Cancer Hospital, Shanghai, People's Republic of China aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/1(2011-01-01), 233-238 1068-9265 18:1<233 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer