caa a22 4500 445333286 CHVBK 20180317142744.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1245/s10434-010-1517-y doi (NATIONALLICENCE)springer-10.1245/s10434-010-1517-y Laparoscopic Versus Open Gastric Resections for Primary Gastrointestinal Stromal Tumors (GISTs): A Size-Matched Comparison [Elektronische Daten] [Giorgos Karakousis, Samuel Singer, Junting Zheng, Mithat Gonen, Daniel Coit, Ronald DeMatteo, Vivian Strong] Background: Laparoscopic resection of gastric GISTs appears technically feasible and associated with favorable outcomes. Tumor size however frequently plays a role in surgical approach with larger tumors tending toward laparotomy, raising concern that favorable outcomes reported for the laparoscopic approach may reflect this selection bias. Materials and Methods: From a prospectively collected sarcoma database, 155 primary gastric GIST resections were identified (1998-2009); 40 patients underwent successful laparoscopic resection for non-GE junction GIST and were randomly matched (1:1) by tumor size (±2.0cm) to patients with open resection. Clinical and pathologic variables and surgical outcomes were associated with surgery type using conditional logistic regression analyses. Results: The two surgical approaches were comparable for clinical and pathologic variables. Median operating room (OR) time was similar, although median length of stay postsurgery was lower in the laparoscopic versus open group (4 vs. 7days, P=0.002), as was estimated blood loss (EBL) (25 vs. 100ml, P=0.006). There was no operative mortality, and 30-day morbidity was similar. Oncologic outcomes were also similar with no positive microscopic margins, and 1 recurrence in each group with a median follow-up of 34months. There were 13 conversions overall, 5 secondary to tumor location at the GE junction or lesser curve. Conclusions: When matched for tumor size, laparoscopic resection of primary gastric GISTs ≤8cm results in shorter hospital stays with similar OR time while maintaining sound oncologic outcomes compared with open resection. Society of Surgical Oncology, 2011 Karakousis Giorgos Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut Singer Samuel Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut Zheng Junting Department of Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut Gonen Mithat Department of Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut Coit Daniel Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut DeMatteo Ronald Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut Strong Vivian Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut Annals of Surgical Oncology Springer-Verlag 18/6(2011-06-01), 1599-1605 1068-9265 18:6<1599 2011 18 10434 https://doi.org/10.1245/s10434-010-1517-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-010-1517-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Karakousis Giorgos Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut NATIONALLICENCE 700 1- Singer Samuel Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut NATIONALLICENCE 700 1- Zheng Junting Department of Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut NATIONALLICENCE 700 1- Gonen Mithat Department of Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut NATIONALLICENCE 700 1- Coit Daniel Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut NATIONALLICENCE 700 1- DeMatteo Ronald Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut NATIONALLICENCE 700 1- Strong Vivian Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/6(2011-06-01), 1599-1605 1068-9265 18:6<1599 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer