caa a22 4500 445333952 CHVBK 20180317142747.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1245/s10434-011-1611-9 doi (NATIONALLICENCE)springer-10.1245/s10434-011-1611-9 Robotics Versus Laparoscopic Radical Hysterectomy with Lymphadenectomy in Patients with Early Cervical Cancer: A Multicenter Study [Elektronische Daten] [Raffaele Tinelli, Mario Malzoni, Francesco Cosentino, Ciro Perone, Annarita Fusco, Ettore Cicinelli, Farr Nezhat] Background: The aim of this study was to retrospectively compare the safety, morbidity, and recurrence rate of total laparoscopic radical hysterectomy (TLRH) with lymphadenectomy and total robotic radical hysterectomy (RRH) with lymphadenectomy for early cervical carcinoma in a series of 99 consecutive women. Materials and Methods: We studied 99 consecutive patients with FIGO stage Ia1 (LVSI), Ia2, Ib1, Ib2, and IIa cervical cancer, 76 of whom underwent TLRH and 23 underwent RRH with pelvic lymph node dissection. Para-aortic lymphadenectomy, with the superior border of the dissection being the inferior mesenteric artery, was performed in all cases with positive pelvic lymph nodes discovered at frozen section evaluation. Results: The mean blood loss was 157ml in the RRH group (95% confidence interval [95% CI] 50-400) and 95ml in the TLRH group (95% CI 30-500) (not significant [NS]). The median length of hospital stay was 3days in the RRH group (95% CI 2-7) and 4days in the TLRH group (95% CI 3-7) (NS). The mean operating time was 255min for the TLRH group (95% CI 182-415) compared with 323min in the RRH group (95% CI 161-433) (P<0.05). No significant difference was found between the 2groups when comparing the recurrence rate. Conclusions: Robotic radical hysterectomy can be considered a safe and effective therapeutic procedure for managing early-stage cervical cancer without significant differences, if compared with laparoscopic radical hysterectomy, in terms of the recurrence rate and intraoperative and postoperative complications, although multicenter randomized clinical trials with longer follow-up are necessary to evaluate the overall oncologic outcomes of this procedure. Society of Surgical Oncology, 2011 Tinelli Raffaele Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy aut Malzoni Mario Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy aut Cosentino Francesco Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy aut Perone Ciro Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy aut Fusco Annarita Department of Public Health, University Medical School of Bari, Bari, Italy aut Cicinelli Ettore 4th Department of Obstetrics and Gynecology, University Medical School of Bari, Bari, Italy aut Nezhat Farr Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mount Sinai Medical Center, New York, NY, USA aut Annals of Surgical Oncology Springer-Verlag 18/9(2011-09-01), 2622-2628 1068-9265 18:9<2622 2011 18 10434 https://doi.org/10.1245/s10434-011-1611-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-011-1611-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tinelli Raffaele Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy aut NATIONALLICENCE 700 1- Malzoni Mario Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy aut NATIONALLICENCE 700 1- Cosentino Francesco Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy aut NATIONALLICENCE 700 1- Perone Ciro Advanced Gynecological Endoscopy Center, Malzoni Medical Center, Avellino, Italy aut NATIONALLICENCE 700 1- Fusco Annarita Department of Public Health, University Medical School of Bari, Bari, Italy aut NATIONALLICENCE 700 1- Cicinelli Ettore 4th Department of Obstetrics and Gynecology, University Medical School of Bari, Bari, Italy aut NATIONALLICENCE 700 1- Nezhat Farr Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mount Sinai Medical Center, New York, NY, USA aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/9(2011-09-01), 2622-2628 1068-9265 18:9<2622 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer