caa a22 4500 445334568 CHVBK 20180317142750.0 cr unu---uuuuu 170323e20111101xx s 000 0 eng 10.1245/s10434-011-1705-4 doi (NATIONALLICENCE)springer-10.1245/s10434-011-1705-4 Prognostic Value of Computed Tomography for Monitoring Pulmonary Metastases in Soft Tissue Sarcoma Patients after Surgical Management: A Retrospective Cohort Study [Elektronische Daten] [Hwan Cho, Il-Hyung Park, Won Jeong, Ilkyu Han, Han-Soo Kim] Background: The lung is the most common site of metastases in patients with a soft tissue sarcoma. However, surveillance protocol for pulmonary metastasis after surgical management has not been proved. The goal of this retrospective study was to evaluate the prognostic value of computed tomography of the chest in soft tissue sarcoma patients after surgery. Methods: A retrospective study was performed on 176 patients who were followed up with chest computed tomographic (CT) scan or plain chest radiographs for pulmonary metastasis monitoring after surgery. Ninety-six patients were followed up with plain chest radiographs and 80 patients with chest CT scan. Mean duration of follow-up was 55.8months. The Kaplan-Meier method and the log-rank test were used to calculate overall survival rates and survival rate difference between chest CT and plain radiograph cohorts. Results: The overall 5- and 10-year survival rates of 176 patients were 75.6% and 70.3%, respectively. The 5-year survival estimates of 96 patients who were included in the plain radiograph cohort and 80 patients in the chest CT cohort were 74.2% and 76.6%, respectively (P=0.70). Fifty-four patients (30.7%) had pulmonary metastasis. Of the 54 patients, 26 belonged to the plain radiograph cohort and 28 patients belonged to the chest CT cohort. Pulmonary metastasis of chest CT cohort had the tendencies of unilaterality, a smaller number of patients, and management with metastasectomy other than palliative management. The 2- and 4-year survival ratess after detection of pulmonary metastasis were 20.1% and 0% in the plain radiograph cohort and 47.4% and 31.6% in the chest CT cohort (P<0.05). Conclusion: Serial monitoring with chest CT could give rise to early detection of pulmonary metastases, chance for metastasectomy, and eventually survival advantage. Society of Surgical Oncology, 2011 Cho Hwan Department of Orthopaedic Surgery, Kyungpook National University College of Medicine, Daegu, Korea aut Park Il-Hyung Department of Orthopaedic Surgery, Kyungpook National University College of Medicine, Daegu, Korea aut Jeong Won Department of Orthopaedic Surgery, Kyungpook National University College of Medicine, Daegu, Korea aut Han Ilkyu Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea aut Kim Han-Soo Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea aut Annals of Surgical Oncology Springer-Verlag 18/12(2011-11-01), 3392-3398 1068-9265 18:12<3392 2011 18 10434 https://doi.org/10.1245/s10434-011-1705-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-011-1705-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cho Hwan Department of Orthopaedic Surgery, Kyungpook National University College of Medicine, Daegu, Korea aut NATIONALLICENCE 700 1- Park Il-Hyung Department of Orthopaedic Surgery, Kyungpook National University College of Medicine, Daegu, Korea aut NATIONALLICENCE 700 1- Jeong Won Department of Orthopaedic Surgery, Kyungpook National University College of Medicine, Daegu, Korea aut NATIONALLICENCE 700 1- Han Ilkyu Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Han-Soo Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/12(2011-11-01), 3392-3398 1068-9265 18:12<3392 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer