caa a22 4500 445335327 CHVBK 20180317142752.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1245/s10434-011-1717-0 doi (NATIONALLICENCE)springer-10.1245/s10434-011-1717-0 Diffuse Microcalcifications Only of the Thyroid Gland Seen on Ultrasound: Clinical Implication and Diagnostic Approach [Elektronische Daten] [Jung Yoon, Eun-Kyung Kim, Eun Son, Hee Moon, Jin Kwak] Background: To evaluate the clinical implications and diagnostic approach of lesions showing only diffuse microcalcifications on thyroid ultrasound (US). Methods: From January 2004 to January 2011, a total of 31 patients had lesions showing diffuse microcalcifications alone on thyroid US. Among them, 26 patients (M:F ratio 4:22; mean age 37.5years, range 15-56years) who had underwent US-guided fine-needle aspiration biopsy (US-FNAB), subsequent surgery, or follow-up US after 1year after initial US-FNAB were included. Histopathologic results from surgery or US-FNAB were considered as standard reference. Clinical and US features were compared to standard reference. Results: Of the disease of 26 patients, 16 (61.5%) were diagnosed as malignancy and 10 (38.5%) as benign. Seventeen (65.4%) of the 26 patients included were diagnosed as having Hashimoto thyroiditis (HT) on a clinical basis. Eight (80.0%) of the 10 benign lesions were diagnosed as benign on initial US-FNAB, and the remaining 2 lesions (20.0%) were nondiagnostic. All malignant lesions were diagnosed as suspicious for papillary thyroid carcinoma (PTC) or PTC by US-FNAB. Of the US features, presence of pathologic lymph nodes were significantly higher in malignant disease compared to benign findings, 10 (62.5%) to 0 (0.0%) (P=0.003). Conclusions: Diffuse microcalcifications only lesions of the thyroid show high prevalence of PTC and lymphocytic thyroiditis. US-FNAB shows an acceptable performance in lesions showing microcalcifications only on thyroid US. Society of Surgical Oncology, 2011 Yoon Jung Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut Kim Eun-Kyung Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut Son Eun Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut Moon Hee Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut Kwak Jin Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut Annals of Surgical Oncology Springer-Verlag 18/10(2011-10-01), 2899-2906 1068-9265 18:10<2899 2011 18 10434 https://doi.org/10.1245/s10434-011-1717-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-011-1717-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yoon Jung Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Eun-Kyung Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Son Eun Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Moon Hee Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kwak Jin Department of Radiology, Research Institute of Radiological Science, Yonsei University, College of Medicine, Seoul, Korea aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/10(2011-10-01), 2899-2906 1068-9265 18:10<2899 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer