caa a22 4500 445335351 CHVBK 20180317142753.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1245/s10434-011-1706-3 doi (NATIONALLICENCE)springer-10.1245/s10434-011-1706-3 Racial Differences in Survival after Surgical Treatment for Melanoma [Elektronische Daten] [Karen Collins, Ryan Fields, Dadrie Baptiste, Ying Liu, Jeffrey Moley, Donna Jeffe] Background: Surgical-treatment outcomes for melanoma in African Americans are poorly characterized as a result of low incidence of melanoma among African Americans. We examined differences by race in overall and melanoma-specific survival, stratified by receipt of surgical treatment and by specific types of surgical treatment. Methods: Data from the 1973-2004 public-use Surveillance, Epidemiology and End Results Program (SEER) were analyzed by Cox proportional hazard models to compare the effects of surgical treatments on overall and melanoma-specific survival in blacks, whites, and other race, controlling for confounding demographic and tumor-related variables. Results: Of 151,154 patients with first primary melanoma (148,883 whites, 789 blacks and 1,532 other race), 142,653 (94.4%) received surgical treatment. Among patients who received surgical treatment, 10-year melanoma-specific survival was lower in blacks (73%) than in whites (88%) and other race (85%); black patients were at significantly higher risk of overall and melanoma-specific mortality when compared with white (hazard ratio [HR]=1.64, 95% confidence interval [CI] 1.44-1.86, P<0.0001 and HR=1.50, 95% CI 1.25-1.79, P<0.0001, respectively) and with other race (HR=1.55, 95% CI 1.31-1.85, P<0.0001 and HR=1.49, 95% CI 1.16-1.91, P=0.0017, respectively). Blacks who underwent biopsy, wide excision and surgery not otherwise specified were at higher risk of overall mortality compared with whites with the same treatment. Conclusion: Overall and melanoma-specific survival was lower in blacks undergoing surgical treatment for melanoma compared to both whites and other race. Reasons for these disparities remain poorly understood. Society of Surgical Oncology, 2011 Collins Karen Division of Health Behavior Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA aut Fields Ryan Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut Baptiste Dadrie Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA aut Liu Ying Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA aut Moley Jeffrey Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO, USA aut Jeffe Donna Division of Health Behavior Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA aut Annals of Surgical Oncology Springer-Verlag 18/10(2011-10-01), 2925-2936 1068-9265 18:10<2925 2011 18 10434 https://doi.org/10.1245/s10434-011-1706-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-011-1706-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Collins Karen Division of Health Behavior Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Fields Ryan Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA aut NATIONALLICENCE 700 1- Baptiste Dadrie Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Liu Ying Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Moley Jeffrey Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Jeffe Donna Division of Health Behavior Research, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/10(2011-10-01), 2925-2936 1068-9265 18:10<2925 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer