caa a22 4500 44533553X CHVBK 20180317142753.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1245/s10434-011-1728-x doi (NATIONALLICENCE)springer-10.1245/s10434-011-1728-x Summary of Prognostic Factors and Patient Selection for Extrapleural Pneumonectomy in the Treatment of Malignant Pleural Mesothelioma [Elektronische Daten] [Christopher Cao, Tristan Yan, Paul Bannon, Brian McCaughan] Background: Extrapleural pneumonectomy (EPP) has been shown to improve long-term survival outcomes in selected patients with malignant pleural mesothelioma (MPM). The present study aimed to evaluate potential prognostic factors on overall survival for patients who underwent EPP for MPM and to examine the patient selection process in major referral centers that perform EPP. Methods: A systematic review of the current literature was performed using 5 electronic databases. Relevant studies with prognostic data on overall survival for patients with MPM treated by EPP were included for review. Two reviewers independently assessed each included study. Results: A total of 17 studies from 13 institutions containing the most updated and complete data on prognostic factors for patients with MPM who underwent EPP were included for review. A number of quantitative, clinical, and treatment-related factors were identified to have significant impact on overall survival. Conclusions: Patients with nonepithelial MPM and nodal involvement have consistently demonstrated to have a worse prognosis after EPP. Their eligibility as candidates for EPP should be questioned. The preoperative patient selection process currently differs greatly between institutions and should focus on identifying patients with nonepithelial histologic subtypes and nodal involvement to exclude them as EPP surgical candidates in the future. Society of Surgical Oncology, 2011 Cao Christopher The Systematic Review Group, The Baird Institute for Applied Heart and Lung Surgical Research, Sydney, Australia aut Yan Tristan The Systematic Review Group, The Baird Institute for Applied Heart and Lung Surgical Research, Sydney, Australia aut Bannon Paul The Systematic Review Group, The Baird Institute for Applied Heart and Lung Surgical Research, Sydney, Australia aut McCaughan Brian The Systematic Review Group, The Baird Institute for Applied Heart and Lung Surgical Research, Sydney, Australia aut Annals of Surgical Oncology Springer-Verlag 18/10(2011-10-01), 2973-2979 1068-9265 18:10<2973 2011 18 10434 https://doi.org/10.1245/s10434-011-1728-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-011-1728-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cao Christopher The Systematic Review Group, The Baird Institute for Applied Heart and Lung Surgical Research, Sydney, Australia aut NATIONALLICENCE 700 1- Yan Tristan The Systematic Review Group, The Baird Institute for Applied Heart and Lung Surgical Research, Sydney, Australia aut NATIONALLICENCE 700 1- Bannon Paul The Systematic Review Group, The Baird Institute for Applied Heart and Lung Surgical Research, Sydney, Australia aut NATIONALLICENCE 700 1- McCaughan Brian The Systematic Review Group, The Baird Institute for Applied Heart and Lung Surgical Research, Sydney, Australia aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/10(2011-10-01), 2973-2979 1068-9265 18:10<2973 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer