caa a22 4500 445335939 CHVBK 20180317142755.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1245/s10434-010-1415-3 doi (NATIONALLICENCE)springer-10.1245/s10434-010-1415-3 Hepatobiliary Procedures in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy [Elektronische Daten] [Gabriel Glockzin, Philipp Renner, Felix Popp, Marc Dahlke, Philipp von Breitenbuch, Hans Schlitt, Pompiliu Piso] Background: The long-term prognosis of patients with peritoneal malignancies has greatly improved since the introduction of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Nevertheless, CRS can be associated with high postoperative morbidity. In this retrospective study, we analyzed the influence of hepatobiliary surgery as part of CRS on postoperative short-term patient outcome. Methods: Between 2005 and 2008, a total of 63 (25%) of 252 patients with peritoneal surface malignancies undergoing CRS and HIPEC required hepatobiliary surgery. Liver resection was performed in 22, resection of Glisson capsule in 39, and bile duct resection in 2 patients. The mean age of the study population was 49.3 years. Thirty-four patients (54%) were women. Results: Complete macroscopic cytoreduction (CC-0/1) was reached in 59 patients (93.7%). The median hospital stay was 18 days. Twenty-two patients developed minor complications (35%), such as moderate fever, pain, or secondary wound healing. In 21 patients (33%), severe complications occurred, most commonly pancreatitis and abdominal abscess. Three patients (4.8%) developed a biliary leakage. Of these, 2 had to be reoperated. Conclusions: In our experience, hepatobiliary procedures have to be performed in up to one-third of patients and are associated with a low rate of specific complications, such as biliary leakages. Society of Surgical Oncology, 2010 Glockzin Gabriel Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut Renner Philipp Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut Popp Felix Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut Dahlke Marc Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut von Breitenbuch Philipp Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut Schlitt Hans Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut Piso Pompiliu Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut Annals of Surgical Oncology Springer-Verlag 18/4(2011-04-01), 1052-1059 1068-9265 18:4<1052 2011 18 10434 https://doi.org/10.1245/s10434-010-1415-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-010-1415-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Glockzin Gabriel Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut NATIONALLICENCE 700 1- Renner Philipp Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut NATIONALLICENCE 700 1- Popp Felix Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut NATIONALLICENCE 700 1- Dahlke Marc Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut NATIONALLICENCE 700 1- von Breitenbuch Philipp Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut NATIONALLICENCE 700 1- Schlitt Hans Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut NATIONALLICENCE 700 1- Piso Pompiliu Department of Surgery, University Medical Center Regensburg, Regensburg, Germany aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/4(2011-04-01), 1052-1059 1068-9265 18:4<1052 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer