caa a22 4500 445336129 CHVBK 20180317142755.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1245/s10434-010-1251-5 doi (NATIONALLICENCE)springer-10.1245/s10434-010-1251-5 Prospective Randomized Trial of Ligasure Versus Harmonic Hemostasis Technique in Thyroidectomy [Elektronische Daten] [Reza Rahbari, Aarti Mathur, Mio Kitano, Marlon Guerrero, Wen Shen, Quan-Yang Duh, Orlo Clark, Electron Kebebew] Background: Two surgical devices have become popular in thyroid surgery: a bipolar energy sealing system (B) and ultrasonic coagulation (UC). Retrospective and prospective studies have demonstrated that the use of these surgical devices for thyroidectomy compared with conventional thyroidectomy (clamp-and-tie) techniques reduces operative time and cost. We conducted a prospective randomized clinical trial to determine if there is any difference in operative time and cost between B and UC. Materials and Methods: A single-blinded prospective randomized controlled trial was conducted at a tertiary referral center. A total of 90 patients who required a thyroidectomy for thyroid cancer, thyroid nodules, or hyperthyroidism were randomized to either B or UC during thyroidectomy. The operative time and cost of thyroidectomy were compared between the two groups. Results: There was no statistically significant difference in patient age, gender, body mass index, indication for thyroidectomy and thyroid gland weight between the two groups. There was no statistically significant difference in operating room cost or total cost for thyroidectomy between the B and UC groups. There was also no statistically significant difference in the operative time between the B and UC groups (187.6 vs. 184.2min, P=0.48) or in postoperative complication rates. The only statistically significant difference in total cost was between surgeons independent of the device used (P<0.01). Conclusions: In thyroid surgery, total cost and operative time were similar between the two surgical devices used. Society of Surgical Oncology, 2010 Rahbari Reza Endocrine Oncology Section, Surgery Branch, National Cancer Institute, Bethesda, MD, USA aut Mathur Aarti Endocrine Oncology Section, Surgery Branch, National Cancer Institute, Bethesda, MD, USA aut Kitano Mio Endocrine Oncology Section, Surgery Branch, National Cancer Institute, Bethesda, MD, USA aut Guerrero Marlon Department of Surgery, University of Arizona, Tucson, AZ, USA aut Shen Wen Department of Surgery, University of California San Francisco, San Francisco, CA, USA aut Duh Quan-Yang Department of Surgery, University of California San Francisco, San Francisco, CA, USA aut Clark Orlo Department of Surgery, University of California San Francisco, San Francisco, CA, USA aut Kebebew Electron Endocrine Oncology Section, Surgery Branch, National Cancer Institute, Bethesda, MD, USA aut Annals of Surgical Oncology Springer-Verlag 18/4(2011-04-01), 1023-1027 1068-9265 18:4<1023 2011 18 10434 https://doi.org/10.1245/s10434-010-1251-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-010-1251-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rahbari Reza Endocrine Oncology Section, Surgery Branch, National Cancer Institute, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Mathur Aarti Endocrine Oncology Section, Surgery Branch, National Cancer Institute, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Kitano Mio Endocrine Oncology Section, Surgery Branch, National Cancer Institute, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Guerrero Marlon Department of Surgery, University of Arizona, Tucson, AZ, USA aut NATIONALLICENCE 700 1- Shen Wen Department of Surgery, University of California San Francisco, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Duh Quan-Yang Department of Surgery, University of California San Francisco, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Clark Orlo Department of Surgery, University of California San Francisco, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Kebebew Electron Endocrine Oncology Section, Surgery Branch, National Cancer Institute, Bethesda, MD, USA aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/4(2011-04-01), 1023-1027 1068-9265 18:4<1023 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer