caa a22 4500 445336498 CHVBK 20180317142757.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1245/s10434-011-1590-x doi (NATIONALLICENCE)springer-10.1245/s10434-011-1590-x Magnetic Resonance Imaging and Ultrasonography in Predicting Infiltrating Residual Disease after Preoperative Chemotherapy in Stage II-III Breast Cancer [Elektronische Daten] [Valentina Guarneri, Annarita Pecchi, Federico Piacentini, Elena Barbieri, Maria Dieci, Guido Ficarra, Giovanni Tazzioli, Antonio Frassoldati, Rachele Battista, Barbara Canossi, Claudia Mauri, Roberto D'Amico, PierFranco Conte, Pietro Torricelli] Background: This study was designed to evaluate the accuracy of breast magnetic resonance imaging (MRI) and ultrasonography (US) in predicting the extent of breast residual disease after preoperative chemotherapy. Methods: Patients with stage II-III invasive breast tumors who received preoperative chemotherapy and were imaged with post-treatment MRI were included. Histopathological verification was available for all patients. The longest diameter of residual tumor measured with MRI and US has been compared with the infiltrating residual tumor size at pathologic evaluation. Results: A total of 108 patients were enrolled: 59 were imaged with both MRI and US (MRI group), and 49 were imaged with US only (non-MRI group). The non-MRI group was enrolled as an external control to avoid possible bias in the selection of patients. In the MRI group, the means of the deltas between MRI residual tumor size and pathologic size and between US and pathologic size were 0.16cm and −0.06cm respectively (P=not significant). Overall, a discrepancy limited in the interval from −0.5cm to +0.5cm compared with the pathologic size was observed in 54% and 51% of the patients with MRI and US, respectively (P=not significant). The linear correlation between the radiological measurement and pathologic tumor size was r=0.53 for MRI and r=0.66 for breast US. In the non-MRI group, the mean of the deltas between US residual tumor size and pathologic size was 0.06cm, and the linear correlation was r=0.79. Conclusions: In this series of patients, MRI and US do not show significant differences in predicting the breast residual infiltrating tumor after preoperative chemotherapy. Society of Surgical Oncology, 2011 Guarneri Valentina Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut Pecchi Annarita Department of Radiology, Modena University Hospital, Modena, Italy aut Piacentini Federico Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut Barbieri Elena Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut Dieci Maria Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut Ficarra Guido Division of Pathology, Modena University Hospital, Modena, Italy aut Tazzioli Giovanni Department of General Surgery and Surgical Specialties, Modena University Hospital, Modena, Italy aut Frassoldati Antonio Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut Battista Rachele Department of Radiology, Modena University Hospital, Modena, Italy aut Canossi Barbara Department of Radiology, Modena University Hospital, Modena, Italy aut Mauri Claudia Department of Radiology, Modena University Hospital, Modena, Italy aut D'Amico Roberto Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut Conte PierFranco Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut Torricelli Pietro Department of Radiology, Modena University Hospital, Modena, Italy aut Annals of Surgical Oncology Springer-Verlag 18/8(2011-08-01), 2150-2157 1068-9265 18:8<2150 2011 18 10434 https://doi.org/10.1245/s10434-011-1590-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-011-1590-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Guarneri Valentina Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Pecchi Annarita Department of Radiology, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Piacentini Federico Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Barbieri Elena Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Dieci Maria Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Ficarra Guido Division of Pathology, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Tazzioli Giovanni Department of General Surgery and Surgical Specialties, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Frassoldati Antonio Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Battista Rachele Department of Radiology, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Canossi Barbara Department of Radiology, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Mauri Claudia Department of Radiology, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- D'Amico Roberto Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Conte PierFranco Department of Oncology, Hematology and Respiratory Diseases, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 700 1- Torricelli Pietro Department of Radiology, Modena University Hospital, Modena, Italy aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/8(2011-08-01), 2150-2157 1068-9265 18:8<2150 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer