caa a22 4500 44533696X CHVBK 20180317142759.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1245/s10434-010-1485-2 doi (NATIONALLICENCE)springer-10.1245/s10434-010-1485-2 Transverse Mesocolon Invasion in Advanced Gastric Cancer: Should We Reconsider Current T Staging? [Elektronische Daten] [Jong Kim, Seong-Ho Kong, Min Kim, Woo Kim, Hyuk-Joon Lee, Kuhn Lee, Han-Kwang Yang] Background: According to the AJCC/UICC TNM classification, T mesocolon invasion in AGC is classified as T2b or T3 according to the presence or the absence of serosa invasion. However, many authors have considered T mesocolon invasion in AGC as T4. This study was performed to evaluate the appropriate T stage for T mesocolon invasion in AGC. Materials and Methods: From 1996 to 2008, 90 patients underwent curative gastrectomy with T mesocolon excision at the authors' institute under the suspicion of T mesocolon invasion based on surgical findings and without pathologic invasion to any other organ. Histopathologic findings were reviewed to determine whether tumors had invaded the T mesocolon. Survival data of AGC patients registered in the SNUH database (N=9998, from 1986 to 2007) was used as reference data for comparative purposes. Results: A total of 27 patients (30%) had proven histopathological invasion of the T mesocolon, and a significant difference in survival rates was found between these 27 and the remaining 63 (P=.012). As compared with the SNUH database population, the survival rate of T mesocolon invasion patients differed from those of T2b (P<.001) and T3 (P=.043) patients, but was similar to that of T4 patients (P=.218). Furthermore, for N1 stage patients, the survival rate differed from those of T2b (P=.001) and T3 (P=.046) patients, but was similar to that of T4 patients (P=.744). Conclusions: The T stage of T mesocolon invasion in AGC should be revised to AJCC/UICC stage T4, because the survival rate of T mesocolon invasion AGC is lower than that of stage T2b or T3. Society of Surgical Oncology, 2011 Kim Jong Department of Surgery, Seoul National University College of Medicine, Seoul, Korea aut Kong Seong-Ho Department of Surgery, Seoul National University College of Medicine, Seoul, Korea aut Kim Min Department of Pathology, Seoul National University College of Medicine, Seoul, Korea aut Kim Woo Department of Pathology and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea aut Lee Hyuk-Joon Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea aut Lee Kuhn Department of Surgery, Seoul National University College of Medicine, Seoul, Korea aut Yang Han-Kwang Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea aut Annals of Surgical Oncology Springer-Verlag 18/5(2011-05-01), 1274-1281 1068-9265 18:5<1274 2011 18 10434 https://doi.org/10.1245/s10434-010-1485-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-010-1485-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kim Jong Department of Surgery, Seoul National University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kong Seong-Ho Department of Surgery, Seoul National University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Min Department of Pathology, Seoul National University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Woo Department of Pathology and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Lee Hyuk-Joon Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Lee Kuhn Department of Surgery, Seoul National University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Yang Han-Kwang Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/5(2011-05-01), 1274-1281 1068-9265 18:5<1274 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer