caa a22 4500 445336978 CHVBK 20180317142759.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1245/s10434-010-1434-0 doi (NATIONALLICENCE)springer-10.1245/s10434-010-1434-0 Mastectomy and Contralateral Prophylactic Mastectomy Rates: An Institutional Review [Elektronische Daten] [Sameer Damle, Christine Teal, Joanne Lenert, Elizabeth Marshall, Qing Pan, Anita McSwain] Background: Breast conservation surgery (BCS) followed by radiation is as effective as mastectomy for long-term survival and is considered standard of care for early-stage breast cancer. An increasing number of patients are opting for cancer-side mastectomies (CM) and often contralateral prophylactic mastectomies (CPM). Our study investigates if there are increasing trends in our patient population toward CM and CPM and identifies common factors associated with those electing to have more extensive surgery. Methods: A retrospective analysis was performed on 812 breast cancer surgeries between January 2001 and December 2009 at The George Washington University Breast Care Center. BCS-eligible patients who elected to have BCS were compared with those who chose CM. Patients who underwent CM were compared with patients undergoing CM and CPM. Results: A personal or family history of breast cancer and larger tumor size were positively associated with choosing CM in BCS-eligible patients. A nonstatistically significant trend toward CM was seen in younger patients. Age, family history, fewer children, Caucasian race, and reconstructive surgery were positively associated with choosing CPM. Conclusion: Mastectomy rates at this institution have not shown the recent sharp increase observed by some authors. The association of age, race, family history, and parity with CPM has been corroborated in multiple studies. However, there is disagreement between statistically significant findings among investigators evaluating factors associated with CPM, and there is limited data in the literature characterizing BCS-eligible patients who chose CM. Larger prospective studies are necessary to further evaluate CM and CPM rates. Society of Surgical Oncology, 2010 Damle Sameer Department of Surgery, Breast Care Center, The George Washington University, Washington, DC, USA aut Teal Christine Department of Surgery, Breast Care Center, The George Washington University, Washington, DC, USA aut Lenert Joanne Department of Surgery, Division of Plastic Surgery, The George Washington University, Washington, DC, USA aut Marshall Elizabeth Department of Surgery, Division of Plastic Surgery, The George Washington University, Washington, DC, USA aut Pan Qing Department of Statistics, Biostatistics Center, The George Washington University, Washington, DC, USA aut McSwain Anita Department of Surgery, Breast Care Center, The George Washington University, Washington, DC, USA aut Annals of Surgical Oncology Springer-Verlag 18/5(2011-05-01), 1356-1363 1068-9265 18:5<1356 2011 18 10434 https://doi.org/10.1245/s10434-010-1434-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-010-1434-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Damle Sameer Department of Surgery, Breast Care Center, The George Washington University, Washington, DC, USA aut NATIONALLICENCE 700 1- Teal Christine Department of Surgery, Breast Care Center, The George Washington University, Washington, DC, USA aut NATIONALLICENCE 700 1- Lenert Joanne Department of Surgery, Division of Plastic Surgery, The George Washington University, Washington, DC, USA aut NATIONALLICENCE 700 1- Marshall Elizabeth Department of Surgery, Division of Plastic Surgery, The George Washington University, Washington, DC, USA aut NATIONALLICENCE 700 1- Pan Qing Department of Statistics, Biostatistics Center, The George Washington University, Washington, DC, USA aut NATIONALLICENCE 700 1- McSwain Anita Department of Surgery, Breast Care Center, The George Washington University, Washington, DC, USA aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/5(2011-05-01), 1356-1363 1068-9265 18:5<1356 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer