caa a22 4500 445338539 CHVBK 20180317142804.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1245/s10434-011-1783-3 doi (NATIONALLICENCE)springer-10.1245/s10434-011-1783-3 Staging of Papillary Thyroid Carcinoma with Ultrasonography: Performance in a Large Series [Elektronische Daten] [Ji Choi, Woong Chung, Jin Kwak, Hee Moon, Min Kim, Eun-Kyung Kim] Background: This study was designed to evaluate the performance of ultrasonography (US) for the preoperative staging of papillary thyroid carcinoma (PTC) in a large series according to the TNM classification. Methods: Preoperative US was performed for the evaluation of primary tumors and lymph node metastasis in 722 consecutive patients with cytologically proven PTC. Three experienced radiologists prospectively determined T and N categories of PTC. N categorization was based on compartments, including left and right lateral compartments (levels II-V) and central compartment (level VI). All patients underwent surgery and central compartment dissection. Lateral compartment dissection was selectively performed. We assessed the diagnostic performance of preoperative US for staging of PTC on the basis of pathologic findings of surgical specimens. Subgroup analysis according to suspicion of diffuse thyroid disease (DTD) on US was performed to compare US accuracies for N categorization. Results: US predicted 61.7% (142/230) of patients with multifocal PTC and 67.1% (100/149) of patients with bilateral malignancy. Overall accuracy of US for T categorization was 69.7% (503/722) and that of US for N categorization was 59% (426/722). Accuracies of sonographic categorization for N0, N1a, and N1b were 66% (276/418), 33.3% (70/210), and 85.1% (80/94), respectively. Overall US accuracy for prediction of an N category was significantly lower in patients with US-indicated DTD (51.1%, 67/131) than it was in patients without DTD (60.7%, 359/591; P=0.043). Conclusions: Preoperative US is a feasible technique for the preoperative staging of PTC and is helpful for the detection of lateral compartment metastasis. Presence of DTD can affect the staging of lymph node metastasis. Society of Surgical Oncology, 2011 Choi Ji Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut Chung Woong Department of Surgery, Yonsei University College of Medicine, Seoul, Korea aut Kwak Jin Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut Moon Hee Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut Kim Min Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut Kim Eun-Kyung Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut Annals of Surgical Oncology Springer-Verlag 18/13(2011-12-01), 3572-3578 1068-9265 18:13<3572 2011 18 10434 https://doi.org/10.1245/s10434-011-1783-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-011-1783-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Choi Ji Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Chung Woong Department of Surgery, Yonsei University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kwak Jin Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Moon Hee Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Min Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Eun-Kyung Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/13(2011-12-01), 3572-3578 1068-9265 18:13<3572 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer