caa a22 4500 445338784 CHVBK 20180317142805.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1245/s10434-011-1792-2 doi (NATIONALLICENCE)springer-10.1245/s10434-011-1792-2 Oncologic Impact of the Curettage of Grade 2 Central Chondrosarcoma of the Extremity [Elektronische Daten] [Wan Cho, Won Song, Dae-Geun Jeon, Chang-Bae Kong, Jae-Soo Koh, Jeung Kim, Soo-Yong Lee] Background: Wide excision is considered the standard treatment for high-grade chondrosarcoma, but little is known regarding the effect of curettage on patient outcome in grade 2 chondrosarcoma. Methods: The records of 32 patients with nonmetastatic grade 2 central chondrosarcoma of the appendicular skeleton were analyzed. The clinical characteristics and outcomes of 15 patients who underwent curettage (the case group) followed by subsequent treatment and 17 patients who underwent standard treatment were compared. The mean follow-up period for all 32 patients was 110months (range, 31-230months). Results: Cases had a smaller tumor volume at presentation (P=.02), a lower Enneking's stage IIA (P<.01), a lower rate of biopsy (P<.01), and a lower incidence of chondroid calcification by plain radiography (P<.01) than controls. Of the 32 study subjects, 2 (1 in the each group) developed local recurrence. The 10-year overall and metastasis-free survival rates for all 32 chondrosarcomas were 84.6%±14.5% and 70.3%±16.5%, respectively. Event-free survivals were similar for cases and controls (P=.16). Conclusions: Intracompartmental grade 2 chondrosarcoma with nonaggressive radiologic pattern have a chance of curettage. However, proper subsequent management achieves outcomes comparable with those of primary wide excision. Society of Surgical Oncology, 2011 Cho Wan Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut Song Won Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut Jeon Dae-Geun Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut Kong Chang-Bae Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut Koh Jae-Soo Department of Pathology, Korea Cancer Center Hospital, Seoul, Korea aut Kim Jeung Department of Orthopedic Surgery, Pusan National University Medical School, Pusan, Korea aut Lee Soo-Yong Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut Annals of Surgical Oncology Springer-Verlag 18/13(2011-12-01), 3755-3761 1068-9265 18:13<3755 2011 18 10434 https://doi.org/10.1245/s10434-011-1792-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-011-1792-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cho Wan Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Song Won Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Jeon Dae-Geun Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Kong Chang-Bae Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Koh Jae-Soo Department of Pathology, Korea Cancer Center Hospital, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Jeung Department of Orthopedic Surgery, Pusan National University Medical School, Pusan, Korea aut NATIONALLICENCE 700 1- Lee Soo-Yong Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/13(2011-12-01), 3755-3761 1068-9265 18:13<3755 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer