caa a22 4500 445339292 CHVBK 20180317142806.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1245/s10434-011-1917-7 doi (NATIONALLICENCE)springer-10.1245/s10434-011-1917-7 Contralateral Prophylactic Mastectomy: Long-Term Consistency of Satisfaction and Adverse Effects and the Significance of Informed Decision-Making, Quality of Life, and Personality Traits [Elektronische Daten] [Marlene Frost, Tanya Hoskin, Lynn Hartmann, Amy Degnim, Joanne Johnson, Judy Boughey] Purpose: This study aims to evaluate the long-term consistency of satisfaction with contralateral prophylactic mastectomy (CPM) and adverse psychosocial effects as well as to explore the effect of informed decision-making, personality traits, and quality of life (QOL) on satisfaction. Methods: A previously established cohort of women with unilateral breast cancer who had undergone CPM between 1960 and 1993 were surveyed using study-specific and standardized questionnaires at two follow-up time points. The first survey was a mean of 10.7years and the second survey a mean of 20.2years after CPM. Results: 487 of the 583 women who responded to the first study were alive and resurveyed. Data from both surveys were available for 269 women. With longer follow-up, there was a small increase in the percentage of women satisfied (90%) and those who would choose CPM again (92%) (4% and 2% increase from first survey, respectively). Most adversely affected were body appearance (31%), feelings of femininity (24%), and sexual relationships (23%). Ninety-three percent of women felt they had made an informed decision. Perception of making an informed choice and current QOL were moderately associated with satisfaction with CPM (r=0.37 and 0.37, respectively) while associations with trait anxiety and optimism were weak (r=0.27 and 0.21, respectively). Conclusions: Long-term satisfaction and adverse effects remained remarkably stable. It is important that women fully understand the benefits and adverse effects associated with CPM. Society of Surgical Oncology, 2011 Frost Marlene Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA aut Hoskin Tanya Division of Biostatistics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA aut Hartmann Lynn Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA aut Degnim Amy Department of Surgery, Mayo Clinic, Rochester, MN, USA aut Johnson Joanne Cancer Center, Mayo Clinic, Rochester, MN, USA aut Boughey Judy Department of Surgery, Mayo Clinic, Rochester, MN, USA aut Annals of Surgical Oncology Springer-Verlag 18/11(2011-10-01), 3110-3116 1068-9265 18:11<3110 2011 18 10434 https://doi.org/10.1245/s10434-011-1917-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1245/s10434-011-1917-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Frost Marlene Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Hoskin Tanya Division of Biostatistics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Hartmann Lynn Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Degnim Amy Department of Surgery, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Johnson Joanne Cancer Center, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Boughey Judy Department of Surgery, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 773 0- Annals of Surgical Oncology Springer-Verlag 18/11(2011-10-01), 3110-3116 1068-9265 18:11<3110 2011 18 10434 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer