caa a22 4500 445339799 CHVBK 20180317142808.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00436-011-2670-3 doi (NATIONALLICENCE)springer-10.1007/s00436-011-2670-3 New insight into praziquantel against various developmental stages of schistosomes [Elektronische Daten] [Wei Wu, Wei Wang, Yi-xin Huang] Praziquantel, due to high efficacy, excellent tolerability, few and transient side effects, simple administration, and competitive cost, is virtually the only drug of choice for treatment of human schistosomiasis. Treatment of schistosomiasis has shown great advances with the introduction of the drug into the therapeutic arsenal in areas that are endemic for the parasite. However, the drug presents various efficacies against different developmental stages of schistosomes, appearing an oddity intermitted mode. The present review article reviews the effects and mechanism of action of praziquantel against schistosomes briefly and suggests the research on this oddity phenomenon. Springer-Verlag, 2011 Wu Wei Jiangsu Institute of Parasitic Diseases, 117 Yangxiang, Meiyuan, 214064, Wuxi, People's Republic of China aut Wang Wei Jiangsu Institute of Parasitic Diseases, 117 Yangxiang, Meiyuan, 214064, Wuxi, People's Republic of China aut Huang Yi-xin Jiangsu Institute of Parasitic Diseases, 117 Yangxiang, Meiyuan, 214064, Wuxi, People's Republic of China aut Parasitology Research Springer-Verlag 109/6(2011-12-01), 1501-1507 0932-0113 109:6<1501 2011 109 436 https://doi.org/10.1007/s00436-011-2670-3 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00436-011-2670-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wu Wei Jiangsu Institute of Parasitic Diseases, 117 Yangxiang, Meiyuan, 214064, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- Wang Wei Jiangsu Institute of Parasitic Diseases, 117 Yangxiang, Meiyuan, 214064, Wuxi, People's Republic of China aut NATIONALLICENCE 700 1- Huang Yi-xin Jiangsu Institute of Parasitic Diseases, 117 Yangxiang, Meiyuan, 214064, Wuxi, People's Republic of China aut NATIONALLICENCE 773 0- Parasitology Research Springer-Verlag 109/6(2011-12-01), 1501-1507 0932-0113 109:6<1501 2011 109 436 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer