caa a22 4500 445340223 CHVBK 20180317142810.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s00436-011-2306-7 doi (NATIONALLICENCE)springer-10.1007/s00436-011-2306-7 Screening for feeding deterrent activity of herbal extracts against the larvae of malaria vector Anopheles subpictus Grassi [Elektronische Daten] [Gandhi Elango, Abdul Rahuman, Chinnaperumal Kamaraj, Asokan Bagavan, Abdul Zahir] This no-choice, laboratory study focuses on the feeding of homogeneous powdered, dried, yeast with different plant extracts on mosquito fourth-instar larvae to determine the effects on their mortality. Screening for antifeedant activity of plant extracts with some known medicinal attributes could lead to the discovery of new agents for vector control. The aim of this study was to investigate the antifeedant activity of crude leaf hexane, ethyl acetate, acetone, and methanol extracts of Andrographis lineata Wallich ex Nees. (Acanthaceae), Anisomeles malabarica (L.) Sims. (Lamiaceae), Argemone mexicana L. (Papaveraceae), Aristolochia bracteolata Lam. (Aristolochiaceae), Chrysanthemum indium L. (Asteraceae), Datura metal L. (Solanaceae), Eclipta prostrata L. (Asteraceae), and Sesbania grandiflora (L.) Pers. (Fibaceae) against the fourth-instar larvae of Anopheles subpictus Grassi (Diptera:Culicidae). All the crude extracts showed antifeedant activity in a dose-dependent manner. The plant extracts exhibited a significant antifeedant activity after 24 and 48h of exposure; however, the highest larval mortality was found in leaf ethyl acetate extract of A. malabarica, acetone extract E. prostrata, methanol extract of A. lineata, C. indium, and S. grandiflora after 24h (LC50 = 2.53, 2.82, 2.31, 2.56, and 2.08mg/mL; LC90 = 6.40, 8.06, 7.45, 6.98, and 6.20mg/mL), respectively. The hexane extract of A. lineata, D. metal, methanol extract of A. bracteolata and E. prostrata showed larval mortality after 48h (LC50 = 3.05, 2.11, 3.00, and 2.18mg/mL; LC90 = 9.06, 6.22, 8.23, and 5.77mg/mL), respectively. One hundred percent larval mortality was observed in methanol extract of A. lineata, and C. indium after 24h and the hexane extract of A. lineata and D. metal after 48h at 10mg/100mL. The methanol extracts of A. lineata and C. indium significantly increased larval mortality in comparison to larvae fed with untreated diet. Bacillus thuringiensis subsp. israelensis is widely accepted as a biological pesticide because of its highly specific activity against dipteran insects without adverse effects on other organisms. The feeding deterrent activity of different herbal extracts against the larvae of malaria vector A. subpictus exhibited significantly lower toxicity compare with the bio larvicides, B. thuringiensis. These results suggest that the methanol extract of A. lineata, C. indium, the hexane extract of A. lineata and D. metal have the potential to be used as an ideal eco-friendly approach for the control of the medically important vector A. subpictus. These findings corroborate traditional insecticidal application of selected plants and the results can be extended for the control of mosquitoes. Springer-Verlag, 2011 Elango Gandhi Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut Rahuman Abdul Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut Kamaraj Chinnaperumal Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut Bagavan Asokan Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut Zahir Abdul Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut Parasitology Research Springer-Verlag 109/3(2011-09-01), 715-726 0932-0113 109:3<715 2011 109 436 https://doi.org/10.1007/s00436-011-2306-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00436-011-2306-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Elango Gandhi Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut NATIONALLICENCE 700 1- Rahuman Abdul Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut NATIONALLICENCE 700 1- Kamaraj Chinnaperumal Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut NATIONALLICENCE 700 1- Bagavan Asokan Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut NATIONALLICENCE 700 1- Zahir Abdul Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, 632 509, Melvisharam, Vellore District, Tamil Nadu, India aut NATIONALLICENCE 773 0- Parasitology Research Springer-Verlag 109/3(2011-09-01), 715-726 0932-0113 109:3<715 2011 109 436 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer